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      • Pediatric sepsis is generally considered to comprise a spectrum of disorders that result from infection by bacteria, viruses, fungi, or parasites or the toxic products of these microorganisms.
      emedicine.medscape.com › article › 972559-overview
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  2. May 9, 2023 · Pediatric sepsis is associated with high mortality and morbidity and requires a high level of awareness and suspicion for early diagnosis and timely treatment. Rapid and careful fluid resuscitation, antibiotic administration, and early vasoactive support are critical to reversing shock.

  3. Specifically, the Third International Consensus Definitions for Sepsis and Septic Shock (Balamuth 2022) stresses that sepsis is a function of 4 variables, namely: threat to life. organ dysfunction (using pSOFA score) dysregulated host response. presence of highly suspected or documented infection.

  4. May 25, 2022 · The Sepsis-3 definition of sepsis is infection in the presence of a greater than or equal to 2-point score increase of the Sequential Organ Failure Assessment (SOFA) score; and septic shock is the presence of hypotension and inotrope requirement in the presence of increased lactate (≥2 mmol/L).

    • Morin, Luc
  5. As with adults, when babies and children develop an infection, their immune systems fight the invading culprit, whether it’s bacteria, a virus, or a fungus. But sometimes the immune system’s response to an infection can spin out of control, leading to a life-threatening condition called sepsis. Sepsis occurs when the body’s response to an ...

  6. Pediatric Sepsis. Key Points: . Sepsis is an overwhelming and life-threatening response to an infection that can cause dysfunction of multiple organ systems. In pediatrics, diagnosing sepsis is especially challenging as children can compensate for severe illness for prolonged periods.

  7. May 9, 2023 · Pediatric sepsis remains an important cause of morbidity and mortality in children. This review will summarize the main aspects of the definition, the current evidence base for interventions discuss some controversial themes and point towards possible areas of improvement.

  8. Nov 23, 2021 · The common causative organisms for sepsis in children vary based on age, underlying condition as well as geographical location. While the most frequently identified pathogens are bacteria and viruses; fungi and parasites can also cause sepsis.

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    Elevate care in critical conditions with our SIRS, Sepsis, and Septic Shock Calculator. Navigate sepsis diagnosis with the SIRS, Sepsis, and Septic Shock Criteria Calculator.

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