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  1. www.ncbi.nlm.nih.gov › pmc › articlesDetecting Tumor Metastases: The Road to Therapy Starts Here

    Abstract. Metastasis is the complex process by which primary tumor cells migrate and establish secondary tumors in an adjacent or distant location in the body. Early detection of metastatic disease and effective therapeutic options for targeting these detected metastases remain impediments to effectively treating patients with advanced cancers.

    • Fig. 2

      Melanoma (A and E), breast cancer (B and F), and PCa...

    • PMC Free Article

      A useful model system for defining the genetic and...

    • A Meta-Analysis

      Study inclusion and exclusion criteria. Inclusion criteria...

  2. www.ncbi.nlm.nih.gov › pmc › articlesCurrent biomarkers of canine mammary tumors - PMC

    Oct 29, 2018 · Due to the high similarity of canine mammary tumors (CMT) to human breast cancers (HBC), human biomarkers of HBC are also detectable in cases of CMT. The evaluation of biomarkers enables clinical diagnoses, treatment options and prognosis for bitches suffering from this disease.

    • Ilona Kaszak, Anna Ruszczak, Szymon Kanafa, Kamil Kacprzak, Magdalena Król, Piotr Jurka
    • 2018

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  4. www.tandfonline.com › doi › fullFull article: Progression of the role of CRYAB in signaling ...

    Aug 18, 2023 · This article reviews the regulation of CRYAB in the apoptotic inflammatory signaling pathway and its role in cancers progression and as a key role in anti-cancer therapy targeting CRYAB in an effort to improve outcomes for patients with metastatic disease.

  5. www.ncbi.nlm.nih.gov › pmc › articlesThe role of CRYAB in tumor prognosis and immune infiltration ...

    Jan 13, 2023 · CRYAB is a crucial component of the TME and influences immune cell infiltration, making it a promising biomarker to assess immune infiltration and prognosis in many malignancies. Keywords: CRYAB, prognosis, immune infiltration, tumor microenvironment, pan-cancer. Go to: Introduction.

    • 10.3389/fsurg.2022.1117307
    • 2022
    • Front Surg. 2022; 9: 1117307.

  6. www.mdpi.com › 2673/5261/3-4 › 25Comprehensive Review of Metastatic Breast Carcinoma in ... - MDPI

    Nov 7, 2022 · In breast carcinoma, biomarker conversion at metastatic sites from the primary breast carcinoma is reported in up to 16% for estrogen receptors (ER) and 10% for human epidermal growth factor receptors-2 (HER-2), which necessitates the revision of therapeutic intervention [ 59, 60 ].

    • Is CRYAB a useful marker for the detection of metastatic carcinoma in dogs?1
    • Is CRYAB a useful marker for the detection of metastatic carcinoma in dogs?2
    • Is CRYAB a useful marker for the detection of metastatic carcinoma in dogs?3
    • Is CRYAB a useful marker for the detection of metastatic carcinoma in dogs?4
    • Is CRYAB a useful marker for the detection of metastatic carcinoma in dogs?5

  7. link.springer.com › article › 10Clinical practice guidelines for molecular tumor markers, 2nd ...

    Nov 29, 2023 · With advances in gene and protein analysis technologies, many target molecules that may be useful in cancer diagnosis have been reported. Therefore, the “Tumor Marker Study Group” was established in 1981 with the aim of “discovering clinically” useful molecules. Later, the name was changed to “Japanese Society for Molecular Tumor Marker Research” in 2000 in response to the ...

  8. link.springer.com › chapter › 10Diagnostic Approach According to More Frequent Metastatic ...

    Jan 1, 2022 · The determination of primary focus in metastasis is crucial. CDX2 and SATB2 for colorectal, TTF-1 and Napsin-A for lung, GCDFP-15 and GATA-3 for breast, and PSA, PSAP, and NKX3.1 for prostate carcinomas are the most useful site-specific biomarkers. Most metastatic...