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We presently overview various preclinical and clinical in vitro and in vivo assays developed to more efficiently detect tumor metastases, which provides the foundation for developing more effective therapies for this invariably fatal component of the cancerous process. Go to: 1. INTRODUCTION.
- M.E. Menezes, S.K. Das, I. Minn, L. Emdad, X.-Y. Wang, D. Sarkar, M.G. Pomper, P.B. Fisher
- 10.1016/bs.acr.2016.07.001
- 2016
- 2016
Apr 5, 2018 · The useful markers in women for MPMs are Calretinin and probably D2-40 (which may be positive in some cases of serous carcinoma) and MOC-31, BG8 (less specific) and BerEP4 in favour of ADCs. In men, the useful markers for MPM are Calretinin, WT1 (nuclear reactivity) and D2-40.
- Janick Selves, Elodie Long-Mira, Marie-Christine Mathieu, Philippe Rochaix, Marius Ilié
- 10.3390/cancers10040108
- 2018
- Cancers (Basel). 2018 Apr; 10(4): 108.
- Suggested decision-tree/diagnostic schema for initial staging (if appropriate) Full size image. Regarding response assessment, the ESMO guidelines suggest repeating initial imaging of target lesions every 8–16 weeks in patients treated with endocrine therapy and every 2–4 cycles for those treated with chemotherapy [10].
- Suggested decision-tree /diagnostic schema for assessing treatment response (restaging) Full size image. BS with technicium-99 m methylene diphosphonate (99mTc-MDP) remains the mainstay of osseous metastatic disease evaluation [14].
- 45-year-old female with multifocal grade 2 invasive ER positive HER2 negative metastatic lobular breast cancer: 99m Tc MDP planar bone scan (a, b) and coronal maximum intensity projection PET/CT (c) show no uptake in the axial or appendicular skeleton.
- Pseudocirrhosis of the liver in 59-year-old female with relapsed grade 3 ER positive HER2 negative metastatic invasive ductal carcinoma of the left breast.
May 30, 2019 · CRYAB was highly expressed in gastric cancer tissues, contributed to gastric cancer cells migration and invasion via EMT, mediated via the NF-κB signaling pathway, predicting a poor prognosis in patients with gastric cancer and, thus, possibly providing a novel therapeutic target for gastric cancer. 124.
- JunFei Zhang, Jia Liu, JiaLi Wu, WenFeng Li, ZhongWei Chen, LiShan Yang
- 10.2147/OTT.S201799
- 2019
- Onco Targets Ther. 2019; 12: 4129-4139.
Mar 24, 2021 · In this Review, we aim to (1) rationalize why cancer metastasis should be a principal consideration in future cancer drug development, (2) appraise the therapies that have and have not worked in...
- Mark Esposito, Shridar Ganesan, Yibin Kang, Yibin Kang, Yibin Kang
- 2021
May 30, 2019 · This article reviews the regulation of CRYAB in the apoptotic inflammatory signaling pathway and its role in cancers progression and as a key role in anti-cancer therapy targeting CRYAB in an effort to improve outcomes for patients with metastatic disease.
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Oct 29, 2018 · CRYAB was found to have the highest specificity and moderate sensitivity for CTC detection . To understand the usefulness of these promising markers, further studies are required. However, CRYAB appears to be a good marker for detection of CTCs in dogs with metastasis of CMT.
