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      • Beyond its critical function in calcium homeostasis, vitamin D has recently been found to play an important role in the modulation of the immune/inflammation system via regulating the production of inflammatory cytokines and inhibiting the proliferation of proinflammatory cells, both of which are crucial for the pathogenesis of inflammatory diseases.
      pubmed.ncbi.nlm.nih.gov › 24971027
  1. Aug 30, 2023 · Vitamin D is a fat-soluble vitamin with many functions in the body. Specifically, it promotes calcium absorption, helps with bone growth, modulates cell growth, plays a role in the immune system, and reduces inflammation.

    • 5 min
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  3. Aug 15, 2022 · Researchers investigated the effects of vitamin D on systematic low-grade inflammation. They found that vitamin D deficiency leads to higher levels of inflammatory biomarkers.

    • Annie Lennon
  4. Jul 18, 2023 · New research has found that older adults with vitamin D deficiency have higher inflammation, and may thus be more at risk of inflammatory diseases. Supplements could help decrease that risk.

  5. Vitamin D has proposed anti-inflammatory properties, yet the role of vitamin D supplementation in reducing inflammation remains largely unknown. The purpose of this review is to investigate the impact of vitamin D supplementation on inflammation, and to identify relevant knowledge gaps in the field.

    • Aya Mousa, Marie Misso, Helena Teede, Robert Scragg, Barbora de Courten
    • 2016
  6. Aug 29, 2022 · Vitamin D target genes present a key role in the action of vitamin D in innate and adaptive immunity, and each function is demonstrated based on particular gene regulatory scenarios.

    • 10.3390/ijms23179784
    • 2022/09
    • Int J Mol Sci. 2022 Sep; 23(17): 9784.
  7. Jan 29, 2015 · Vitamin D tends to modestly lower markers of inflammation in highly inflammatory conditions, when baseline 25 (OH)D levels were low and when achieved 25 (OH)D levels were higher.

  8. Jul 22, 2014 · Research points to a bacterial etiology pathogenesis for an inflammatory disease process which results in high 1,25 (OH)2D and low 25 (OH)D. Immunotherapy, directed at eradicating persistent intracellular pathogens, corrects dysregulated vitamin D metabolism and resolves inflammatory symptoms.

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