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  2. Sep 11, 2023 · One of the main differences is that hemophilia primarily affects males, whereas VWD affects both females and males. Another difference is that VWD tends to be milder than hemophilia....

  3. Apr 29, 2021 · Although that may be true for mild VWD patients, specific comparative studies revealed that the bleeding profile between VWD-type 3 and severe hemophilia A is more similar than expected. 4,5 Nevertheless, prophylactic treatment remains relatively rare in VWD patients.

    • Cécile V Denis, Sophie Susen, Peter J Lenting
    • 2021
  4. Dec 19, 2022 · Another difference: Men and women have an equal chance of getting VWD, whereas hemophilia is much rarer in women than in men. And compared with hemophilia, people with VWD are less likely to bleed into their joints. VWD most often causes easy bruising and nosebleeds, and women with VWD can experience very heavy menstrual periods.

  5. Jan 11, 2021 · The American Society of Hematology (ASH), the International Society on Thrombosis and Haemostasis (ISTH), National Hemophilia Foundation (NHF), and World Federation of Hemophilia (WFH) have developed joint clinical practice guidelines on the diagnosis and management of von Willebrand disease (VWD), the world’s most common inherited bleeding disorder.

  6. Feb 1, 2024 · VWD occurs when a quantitative or qualitative abnormality of VWF leads to defects in primary hemostasis and, depending on the type and severity, to a subsequent factor VIII deficiency similar to hemophilia. SEVERITY VARIES.

  7. Von Willebrand Disease vs. Hemophilia. People with hemophilia or Type 1 VWD may have low levels of the blood clotting factor VIII (8). However, the big difference between the two bleeding disorders is that people with hemophilia have normal levels of von Willebrand factor.

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