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- DictionaryVon Wil·le·brand's dis·ease/vän ˈviləbränts dəˌzēz/
noun
- 1. an inherited disorder characterized by a tendency to bleed, caused by deficiency or abnormality of a plasma coagulation factor (von Willebrand factor).
Von Willebrand disease ( VWD) is the most common hereditary blood-clotting disorder in humans. An acquired form can sometimes result from other medical conditions. [1] It arises from a deficiency in the quality or quantity of von Willebrand factor (VWF), a multimeric protein that is required for platelet adhesion.
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Von Willebrand disease is a bleeding disorder that slows the blood clotting process, causing prolonged bleeding after an injury. People with this condition often experience easy bruising, long-lasting nosebleeds, and excessive bleeding or oozing following an injury, surgery, or dental work. Mild forms of von Willebrand disease may become ...
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Mar 11, 2024 · Von Willebrand disease is similar to hemophilia, another type of bleeding disorder, though it is a different condition. In a typical injury with a tear in a blood vessel, your dog’s body deploys ...
- Rebekah Kuschmider
Type 1: With Type 1, people still produce von Willebrand factor, but at lower amounts. It’s the mildest and most common form of the condition. Type 2: People with Type 2 make normal or below-normal amounts of von Willebrand clotting factor, but it doesn’t work correctly. The proteins might not be the right size, might try to start clotting ...
Dec 18, 2023 · What to know about Von Willebrand's disease Von Willebrand disease (vWD) is the most common inherited bleeding condition. It can also result from leukemia, lupus, and the use of some drugs.
It is a hormone that causes the body to release more von Willebrand factor into the bloodstream. It is given intravenously (IV), into your child's vein, or into your child's nose with a nasal spray. Another treatment is von Willebrand factor replacement therapy. Certain antifibrinolytic medicines—medicines that prevent blood clots from being ...
Mar 31, 2023 · Practice Essentials. Von Willebrand disease (vWD) is a common, inherited, genetically and clinically heterogeneous hemorrhagic disorder caused by a deficiency or dysfunction of the protein termed von Willebrand factor (vWF). In vWD, defective vWF interaction between platelets and the vessel wall impairs primary hemostasis. [ 1] (.