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    Von Wil·le·brand's dis·ease
    /vän ˈviləbränts dəˌzēz/

    noun

    • 1. an inherited disorder characterized by a tendency to bleed, caused by deficiency or abnormality of a plasma coagulation factor (von Willebrand factor).
  2. Von Willebrand disease ( VWD) is the most common hereditary blood-clotting disorder in humans. An acquired form can sometimes result from other medical conditions. [1] It arises from a deficiency in the quality or quantity of von Willebrand factor (VWF), a multimeric protein that is required for platelet adhesion.

    • .mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}/ˌfʌnˈvɪlɪbrɑːnt/
  3. Von Willebrand disease is a bleeding disorder that slows the blood clotting process, causing prolonged bleeding after an injury. People with this condition often experience easy bruising, long-lasting nosebleeds, and excessive bleeding or oozing following an injury, surgery, or dental work. Mild forms of von Willebrand disease may become ...

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  5. Mar 11, 2024 · Von Willebrand disease is similar to hemophilia, another type of bleeding disorder, though it is a different condition. In a typical injury with a tear in a blood vessel, your dog’s body deploys ...

    • Rebekah Kuschmider
  6. Type 1: With Type 1, people still produce von Willebrand factor, but at lower amounts. It’s the mildest and most common form of the condition. Type 2: People with Type 2 make normal or below-normal amounts of von Willebrand clotting factor, but it doesn’t work correctly. The proteins might not be the right size, might try to start clotting ...

  7. It is a hormone that causes the body to release more von Willebrand factor into the bloodstream. It is given intravenously (IV), into your child's vein, or into your child's nose with a nasal spray. Another treatment is von Willebrand factor replacement therapy. Certain antifibrinolytic medicines—medicines that prevent blood clots from being ...

  8. Mar 31, 2023 · Practice Essentials. Von Willebrand disease (vWD) is a common, inherited, genetically and clinically heterogeneous hemorrhagic disorder caused by a deficiency or dysfunction of the protein termed von Willebrand factor (vWF). In vWD, defective vWF interaction between platelets and the vessel wall impairs primary hemostasis. [ 1] (.

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