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      • Von Willebrand factor acts like glue to help the platelets stick together and form a blood clot. Von Willebrand factor also carries with it clotting factor VIII (8), another important protein that helps your blood clot. Factor VIII is the protein that is inactive or missing in hemophilia, another clotting disorder.
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  2. Oct 26, 2021 · To evaluate you for von Willebrand disease, your doctor will likely ask you detailed questions about your medical history and check for bruises or other signs of recent bleeding. Your doctor will also likely recommend the following blood tests: Von Willebrand factor antigen.

    • What Is Von Willebrand Disease?
    • What Happens If You Have Von Willebrand Disease?
    • How Common Is This condition?

    Von Willebrand disease is a common blood disorder that keeps your blood from clotting. This is an inherited disorder, meaning parents may pass the disorder on to their biological children. Healthcare providers treat this disorder with medication to help with blood clotting.

    People with von Willebrand disease may bleed more than usual. For example, they may have frequent nosebleeds or bleed for a long time after getting a minor cut. Women or people designated female at birth (DFAB) may have heavy menstrual periods or heavy bleeding after giving birth. People who have the most serious form of von Willebrand disease may ...

    Von Willebrand disease affects 1% of the U.S. population and is the most common bleeding disorder in the United States. Globally, von Willebrand disease affects an estimated 23 to 110 in 1 million people. The numbers vary because people may have bleeding issues, but aren’t diagnosed with von Willebrand disease. In some cases, people have had bleedi...

  3. Von Willebrand disease (VWD) is a blood disorder in which the blood does not clot properly. Blood contains many proteins that help the blood clot when needed. One of these proteins is called von Willebrand factor (VWF). People with VWD either have a low level of VWF in their blood or the VWF protein doesn’t work the way it should.

  4. Apr 16, 2024 · In people with VWD, a protein called von Willebrand factor (VWF) is deficient or does not function properly. There are different types of inherited VWD; some cause low levels of VWF, and others cause the production of VWF that does not function correctly. (See 'Types of von Willebrand disease' below.)

  5. Von Willebrand disease (VWD) is an inheritable bleeding disorder. Many different proteins are needed to make a person’s blood clot successfully. People with VWD are either missing or low in the clotting protein von Willebrand factor (VWF) – or it doesn’t work as it’s supposed to.

  6. In VWD, you either have low levels of a certain protein in your blood or the protein doesn't work the way it should. The protein is called von Willebrand factor (VWF). It is made in the walls of your blood vessels and released into your blood. Normally, when one of your blood vessels is injured, you start to bleed.

  7. Mar 31, 2017 · Von Willebrand disease is a bleeding disorder. It’s caused by a deficiency of von Willebrand factor (VWF). This is a type of protein that helps your blood to clot. Von Willebrand is...

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