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Jan 26, 2023 · The pathology of sepsis is tightly associated with dysregulation of innate immune responses. The contribution of macrophages, neutrophils, and dendritic cells to sepsis is well documented, whereas the role of natural killer (NK) cells, which are critical innate lymphoid lineage cells, remains unclear.
Mar 8, 2022 · Neonates have only a limited repertoire of stereotypic reactions to different harmful stimuli either infectious, metabolic, respiratory, or traumatic ( 17) and many symptoms or signs of sepsis can be attributed to non-infectious neonatal disorders ( 18 ).
- 10.3389/fped.2022.840288
- 2022
- Front Pediatr. 2022; 10: 840288.
Jul 22, 2021 · Natural killer cells, one of the important types of innate immune cells, play a pivotal role in the antiviral process in vivo. It has been shown that increasing NK cell activity may promote the alleviation of viral infections, even severe infection-induced sepsis.
- Lu Ma, Qi Li, Suna Cai, Hourong Peng, Ting Huyan, Hui Yang
- 10.7150/ijms.59898
- 2021
- Int J Med Sci. 2021; 18(14): 3236-3248.
Dec 19, 2023 · In inflammatory responses due to severe infections, immune cells undergo various phenotypic changes as the immune system fails to resolve inflammation appropriately.
Nov 2, 2021 · Neonatal sepsis is a clinical syndrome characterized by nonspecific signs and symptoms caused by invasion by pathogens. 1, 2 Sepsis is deemed culture-proven if confirmed by microbial growth on...
- Istemi Han Celik, Morcos Hanna, Fuat Emre Canpolat, Fuat Emre Canpolat, Mohan Pammi
- 2021
However, developing data has shown the importance of NK cells in mounting a potent immune response against invading bacterial pathogens that if not contained accordingly may lead to the development of sepsis.
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Do natural killer cells help with sepsis?
Do neonates have sepsis?
Why is neonatal sepsis important?
How does late onset neonatal sepsis affect a newborn?
Bacterial infections are the most common cause of sepsis in newborns. Bacteria such as E. coli, Listeria and Group B streptococcus (GBS) are common bacteria that can cause infections that lead to sepsis. Viruses, fungi and parasites can also lead to the condition.
