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- The most common problem in hereditary spherocytosis is anemia. Large-scale destruction of RBCs causes visible jaundice. This happens because the large amount of hemoglobin released gets converted to bilirubin. Bilirubin gives a yellow tinge to the whites of the eyes. You also may notice that your skin, tongue, and nails look pale.
www.webmd.com › children › what-is-hereditary-spherocytosisHereditary Spherocytosis: Symptoms, Diagnosis, and Treatment
Hereditary spherocytosis is an inherited blood disorder that causes hemolytic anemia. This anemia happens when your red blood cells break down faster than normal.
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Jul 4, 2023 · Approximately 50% of patients with hereditary spherocytosis present with anemia, and 10 to 15% with splenomegaly or jaundice. The majority of patients will present partially compensating hemolysis in addition to mild anemia.
- Edgar A. Zamora, Catherine A. Schaefer
- 2023/07/04
Jun 9, 2018 · Anemia. Spherocytosis causes your red blood cells to break down faster than healthy cells do, which can lead to anemia. If spherocytosis causes anemia, you may appear paler than...
- Carmella Wint
Feb 16, 2022 · Spherocytosis affects red blood cell structure, causing anemia and an enlarged spleen. It is usually inherited and it can be managed with treatment.
Hereditary spherocytosis is a condition that affects red blood cells. People with this condition typically experience a shortage of red blood cells ( anemia ), yellowing of the eyes and skin (jaundice), and an enlarged spleen (splenomegaly).
Aug 5, 2019 · Consequently, affected individuals do not receive enough oxygen-rich blood (microcytic anemia) throughout the body. Affected individuals may experience classic signs of anemia including fatigue, weakness, shortness of breath, dizziness or headaches. Severe anemia can cause serious, even life-threatening complications if left untreated.
Mar 6, 2023 · Anemia affects the body’s ability to carry oxygen, potentially affecting many areas of functioning. Red blood cells typically live about 120 days before the spleen destroys them.