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Arylcyclohexylamines, also known as arylcyclohexamines or arylcyclohexanamines, are a chemical class of pharmaceutical, designer, and experimental drugs.
Jan 1, 2016 · Arylcyclohexamines (also known as arylcyclohexylamines) are a group of compounds that contain a cyclohexamine unit with an aryl moiety, typically a phenyl ring, attached to the same atom to which the amine group is linked (see Fig. 1). They all exhibit dissociative...
Dec 8, 2022 · Arylcyclohexylamine (ACH) compounds such as ketamine, phencyclidine and eticyclidine derivatives are of particular concern, given their rapidly increasing use and the absence of detailed toxicity data. First used mainly for their pharmacological properties in anesthesia, their recreational use is increasing.
- 10.3390/ijms232415574
- 2022/12
- Int J Mol Sci. 2022 Dec; 23(24): 15574.
Jan 13, 2024 · Arylcyclohexylamines (AKA arylcyclohexan-amines) are a class of dissociative drugs that decouple one’s first-person, conscious experience from objective reality. They isolate self-aware aspects of the mind from sensory and emotional processing.
Apr 6, 2020 · Today, several dissociative designer drugs (Fig. 6) are available, mostly arylcyclohexylamines (e.g., ketamine and PCP) and diarylethylamines. Morris, Wallach, and Brandt previously published comprehensive overviews of the history, availability, and use of several arylcyclohexylamine and diarylethylamine designer drugs and other dissociative ...
- Dino Luethi, Matthias E. Liechti
- 2020
Jun 20, 2023 · Summary. Antihistamines are used to treat allergies. They work by suppressing a chemical called histamine that triggers allergy symptoms like rash, runny nose, watery eyes, and sneezing. They may also be useful in treating motion sickness, nausea, sinusitis, and eczema.
Jan 1, 2022 · Arylcyclohexamines are a group of substances that exhibit dissociative effects due primarily to antagonism of the N-methyl-d-aspartate (NMDA) receptor. Many arylcyclohexamines have been studied in animal and human populations as effective alternatives to traditional inhalational and intravenous anaesthetic agents, and have now become drugs of ...
