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A clue cell is a type of cell found in the vagina, an epithelial cell, that when examined under a microscope is found to have a cluster of bacteria attached to it. 1,2 Clue cells are distinctive in appearance, as they are covered in bacteria and what’s known as a bacterial biofilm .
- ◉ Diagnosis of Clue Cells
- ◉ What Does It Mean If You Have Clue Cells ?
- ◉ What Are Clue Cells Caused by?
- ◉ Is It Normal to Have Some Clue Cells ?
To detect clue cells, a healthcare provider will perform a vaginal exam and collect a sample of vaginal discharge using a sterile swab for microscopy observation. 1. Place the sample on a clean microscope slide by rolling the swab back and forth. 2. Let it dry, then perform a Gram stain. 3. Examine the slide under a microscope using oil immersion a...
Normally, the vagina contains a balance of different types of bacteria that help maintain a healthy environment. The presence of clue cells in a sample of vaginal secretions indicates an abnormal overgrowth of certain types of bacteria and depletion of protective bacteria such as lactobacillus, this is a hallmark of bacterial vaginosis, a common va...
Gardnerella vaginalis is a type of bacteria that is commonly associated with bacterial vaginosis. It is a Gram-variable bacilli or coccobacilli ; catalase and oxidase negative; sodium hippurate hydrolysis positive; acid production from glucose, maltose, and sucrose (variable)
It may indicate the presence of BV. However, the interpretation should be made in conjunction with other clinical and laboratory findings, as the presence of clue cells alone is not sufficient to diagnose BV.
Dec 27, 2023 · Clue cells are vaginal epithelial cells covered with bacteria, making them appear stippled or granulated when viewed under a microscope. In the context of BV, the presence of clue cells is a key diagnostic criterion.
Clue cell. Micrograph of a clue cell (center), covered in bacteria, as compared to an unremarkable squamous cell at bottom left, and a neutrophil at bottom center. Pap stain. Clue cells are epithelial cells of the vagina that get their distinctive stippled appearance by being covered with bacteria. The etymology behind the term "clue" cell ...
Clue cells are identified as vaginal epithelial cells with such a heavy coating of bacteria that the peripheral borders are obscured. If three of four criteria are met, then a clinical diagnosis of BV can be made.
- Deborah Money
- 2005
Feb 22, 2022 · Clue cells describe vaginal cells that, when observed under a microscope, have the characteristics of a bacterial infection. In this instance, the healthcare provider is looking specifically at epithelial cells (the type that line hollow organs).
May 6, 2024 · Since clue cells are a reliable diagnostic sign of bacterial vaginosis, the vaginal discharge can be examined under a microscope. This diagnostic step can also help to rule out the presence of yeast or trichomonads.
