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- The drug or breastfeeding should be discontinued if liver toxicity is suspected.
Aug 1, 2008 · PTU should be discontinued immediately after diagnosis of PTU-induced AAV; immunosuppressive therapy should be administrated only for patients with vital organ involvement, such as lung and kidney vasculitis.
- Y. Gao, M. Chen, H. Ye, F. Yu, X.-h. Guo, M.-h. Zhao
- 2008
People also ask
When should PTU be discontinued?
When should propylthiouracil be discontinued?
How long does PTU last in patients with AAV?
Should a patient be monitored while on PTU therapy?
Jun 5, 2023 · Educate the patients that if there are any new symptoms, PTU should be discontinued immediately. Moreover, depending on the severity of symptoms, patients need to contact the prescribing clinician or go to the emergency department.
- Fnu Amisha, Anis Rehman
- 2023/06/05
The long-term outcomes of patients with PTU-induced AAV were relatively good. PTU should be discontinued immediately after diagnosis. Immunosuppressive therapy may be only used in patients with vital organ involvements, and a long-term maintenance therapy may not be necessary.
- Y. Gao, M. Chen, H. Ye, F. Yu, X.-h. Guo, M.-h. Zhao
- 2008
Propylthiouracil (PTU) is a medication used to treat hyperthyroidism. This includes hyperthyroidism due to Graves' disease and toxic multinodular goiter. In a thyrotoxic crisis it is generally more effective than methimazole. Otherwise it is typically only used when methimazole, surgery, and radioactive iodine is not possible.
Apr 21, 2009 · If patients taking PTU develop tiredness, nausea, anorexia, fever, pharyngitis, or feel ill, the medication should be immediately discontinued by the patient, a physician should be contacted, and a white blood cell count, liver function tests, and transaminase levels obtained.
- Scott A. Rivkees, Donald R. Mattison
- 2009
Jan 3, 2024 · If patients taking propylthiouracil develop tiredness, nausea, anorexia, fever, pharyngitis, or malaise, propylthiouracil should be discontinued immediately by the patient, a physician should be contacted, and a white blood cell count, liver function tests, and transaminase levels obtained.
BACKGROUND. The antithyroid drugs methimazole (MMI) and propylthiouracil (PTU) are used as one option to treat patients with hyperthyroidism, especially those with Graves’ disease. The goal of antithyroid drug treatment is to treat for a defined period of time then stop to determine if the Graves’ disease has gone into remission.
