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  1. Jul 20, 2020 · Pisuviricota accommodated another large clade with 343 RdRPs related to those of Dicistroviridae (order Picornavirales; Fig. 2), which infect marine and terrestrial arthropods 30,46.

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  2. Apr 4, 2023 · Typically, actual full-length viral RdRp core sequences range approximately from 350 to 600 a.a. in length (depending on virus clade). Most of the shorter sequences found derived from the TSA database.

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  4. Jul 20, 2020 · Note that this lineage of permuted RdRPs is confidently lodged as additional clade in Branch 2 (Pisuviricota) as a sister to Partitiviridae lineage. Of the 387 long Yan-like contigs, 220 encode a distinct SJR-CP and 100 encode a capping enzyme.

    • Yuri I Wolf, Sukrit Silas, Yongjie Wang, Shuang Wu, Michael Bocek, Darius Kazlauskas, Mart Krupovic,...
    • 10.1038/s41564-020-0755-4
    • 2020
    • Nat Microbiol. 2020; 5(10): 1262-1270.
  5. Based on phylogenetic analysis of RdRp, all other RNA viruses are considered to comprise a sister clade in relation to Lenarviricota. Pisuviricota False-color Transmission electron micrograph of a SARS-CoV-2 virion. Coronaviruses like SARS-CoV-2 fall in the phylum Pisuviricota.

  6. Apr 8, 2022 · This divides the Riboviria realm into five phyla, based on RdRP amino acid multiple sequence alignments: positive-sense single-stranded Lenarviricota, Pisuviricota (including some double-stranded...

  7. Sep 28, 2022 · Outside of Pisuviricota and Kitrinoviricota, we detected only a small clade consisting of 2 permuted RCR90 RdRPs within Botourmiaviridae (Lenarviricota). Expansion of the protein domain repertoire of RNA viruses

  8. Aug 15, 2022 · The PDB IDs are 1RA6 (Pisuviricota RdRp), 6V85 (Negarnaviricota RdRp), 4GZK (Duplornaviricota RdRp), 2XI2 (Kitrinoviricota RdRp), 4R71 (Lenarviricota RdRp) and 1MU2 (Reverse Transcriptase). The RdRp core domain of 1RA6 comprises residues 139 to 404 of chain A (1RA6:A:139-404) based on the GenBank annotation.

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