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  2. Apr 1, 2019 · A. 42. Risk factors for recurrence of febrile seizure are age younger than 18 months, fever duration of less than one hour before seizure onset, first-degree relative with a history of...

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    Usually, a child having a febrile seizure shakes all over and loses consciousness. Sometimes, the child may get very stiff or twitch in just one area of the body.

    A child having a febrile seizure may:

    •Have a fever higher than 100.4 F (38.0 C)

    •Lose consciousness

    •Shake or jerk the arms and legs

    Febrile seizures are classified as simple or complex:

    See your child's doctor as soon as possible after your child's first febrile seizure, even if it lasts only a few seconds. Call an ambulance to take your child to the emergency room if the seizure lasts longer than five minutes or is accompanied by:

    •Vomiting

    •A stiff neck

    •Breathing problems

    •Extreme sleepiness

    Request an appointment

    Infection

    The fevers that trigger febrile seizures are usually caused by a viral infection, and less commonly by a bacterial infection. The flu (influenza) virus and the virus that causes roseola, which often are accompanied by high fevers, appear to be most frequently associated with febrile seizures.

    Post-vaccination seizures

    The risk of febrile seizures may increase after some childhood vaccinations. These include the diphtheria, tetanus and pertussis vaccine and the measles-mumps-rubella vaccine. A child can develop a low-grade fever after a vaccination. The fever, not the vaccine, causes the seizure.

    Factors that increase the risk of having a febrile seizure include:

    •Young age. Most febrile seizures occur in children between 6 months and 5 years of age, with the greatest risk between 12 and 18 months of age.

    Most febrile seizures produce no lasting effects. Simple febrile seizures don't cause brain damage, intellectual disability or learning disabilities, and they don't mean your child has a more serious underlying disorder.

    Febrile seizures are provoked seizures and don't indicate epilepsy. Epilepsy is a condition characterized by recurrent unprovoked seizures caused by abnormal electrical signals in the brain.

    Giving your child medications

    Giving your child infants' or children's acetaminophen (Tylenol, others) or ibuprofen (Advil, Motrin, others) at the beginning of a fever may make your child more comfortable, but it won't prevent a seizure. Use caution when giving aspirin to children or teenagers. Though aspirin is approved for use in children older than age 3, children and teenagers recovering from chickenpox or flu-like symptoms should never take aspirin. This is because aspirin has been linked to Reye's syndrome, a rare but potentially life-threatening condition, in such children.

    Prescription prevention medications

    Rarely, prescription anticonvulsant medications are used to try to prevent febrile seizures. However, these medications can have serious side effects that may outweigh any possible benefit. Rectal diazepam (Diastat) or nasal midazolam might be prescribed to be used as needed for children who are prone to long febrile seizures. These medications are typically used to treat seizures that last longer than five minutes or if the child has more than one seizure within 24 hours. They are not typically used to prevent febrile seizures. Request an appointment By Mayo Clinic Staff Mar 03, 2023 1.Febrile seizures fact sheet. National Institute of Neurological Disorders and Stroke. https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets/Febrile-Seizures-Fact-Sheet. Accessed Jan. 12, 2021. 2.Millichap JG, et al. Clinical features and evaluation of febrile seizures. https://www.uptodate.com/contents/search. Accessed Jan. 12, 2021. 3.Millichap JG, et al. Treatment and prognosis of febrile seizures. https://www.uptodate.com/contents/search. Accessed Jan. 12, 2021. 4.AskMayoExpert. Febrile seizure (child). Mayo Clinic. 2019. 5.Subcommittee on Febrile Seizures. Febrile seizures: Guideline for the neurodiagnostic evaluation of the child with a simple febrile seizure. American Academy of Pediatrics. 2011; DOI: https://doi.org/10.1542/peds.2010-3318. 6.Wong-Kisiel LC (expert opinion). Mayo Clinic. Jan. 13, 2021. Diagnosis & treatment 1.Diseases & Conditions 2.Febrile seizure symptoms & causes

    •EEG (electroencephalogram)

    •Lumbar puncture (spinal tap)

    •A Book: Mayo Clinic Guide to Your Baby's First Years

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  3. Jan 19, 2024 · The primary febrile seizure risk factors appear to include existing neurologic impairment, the presence of a viral infection, a family history of seizure, developmental delay, decreased serum zinc and iron levels, and maternal smoking and stress.

    • 2024/01/19
  4. Nov 28, 2023 · Certain things increase the risk for more febrile seizures, including: Young age—Children who have their first febrile seizure when they are younger than 18 months are at an increased risk of having another one. Family history—Children whose family members had febrile seizures are more likely to have more than one seizure.

  5. Children with 1 of these risk factors have a 2.5% (1 in 40) chance of later epilepsy. For children with 2 or 3 risk factors, their chance of developing epilepsy later ranges from 5% (1 in 20) to over 10% (greater than 1 in 10). In rare cases, febrile seizures that last more than 30 minutes may cause scar tissue in the temporal lobe of the brain.

  6. Genetic and familial factors appear to increase susceptibility to febrile seizures. Monozygotic twins have a much higher concordance rate than dizygotic twins. Several genes associated with febrile seizures have been identified. Developmental delay increases risk of epilepsy after febrile seizure (1). Reference. 1.

  7. Children at highest risk for recurrence are those who have: their first febrile seizure at a young age (younger than 18 months) a family history of febrile seizures. a febrile seizure as the first sign of an illness. a relatively low temperature that increases with their first febrile seizure.

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  2. Learn more about this treatment and get important FYCOMPA® updates. See if FYCOMPA® (perampanel) CIII is the right treatment for you.

  3. Learn how to access treatment for patients living with Dravet syndrome. Getting your patients' seizures under control is an essential treatment goal.

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