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What is the difference between streptothricin & streptomycin?
What is streptothricin?
Is streptomycin a bactericidal substance?
Feb 7, 2024 · The streptothricin antibiotics were among the first antibiotics to be discovered from the environment and remain some of the most recovered antimicrobials in natural product screens.
Streptomycin is an antibiotic medication used to treat a number of bacterial infections, including tuberculosis, Mycobacterium avium complex, endocarditis, brucellosis, Burkholderia infection, plague, tularemia, and rat bite fever.
Jul 21, 2020 · Tetracycline, streptomycin, kanamycin and gentamicin block protein synthesis by binding to the small ribosomal subunit (30S), whereas erythromycin, clindamycin and chloramphenicol target the large ribosomal subunit (50S). Ciprofloxacin and novobiocin interfere with bacterial DNA translation.
- Gerry A. Quinn, Aiya M. Banat, Alyaa M. Abdelhameed, Ibrahim M. Banat
- 10.1099/jmm.0.001232
- 2020
- J Med Microbiol. 2020 Aug; 69(8): 1040-1048.
May 16, 2023 · Here, we establish the activity spectrum of nourseothricin and its main components, streptothricin F (S-F, 1 lysine) and streptothricin D (S-D, 3 lysines), purified to homogeneity, against highly drug-resistant, carbapenem-resistant Enterobacterales (CRE) and Acinetobacter baumannii.
Dr. Waksman's studies had led to the discovery of streptomycin, a new antibiotic. Streptomycin was the first effective cure for tuberculosis (TB). Its history, however, is a rather complicated story. It persistently presented problems for Dr. Waksman up to his death in 1973.
- H. Boyd Woodruff
- 10.1128/AEM.01143-13
- 2014
- Appl Environ Microbiol. 2014 Jan; 80(1): 2-8.
The patients who did not have such a good outcome had sequestra, thick walled abscesses, or uncontrolled dead spaces, all of which were amenable to surgical intervention because of the effect of streptomycin.
Streptomycin, the world's first "broad spectrum" antibiotic, attacked diverse pathogens including those causing plague, cholera, typhoid, tularemia, brucellosis and dysentery (infections unaffected by penicillin) and also Gram positive pathogens.
