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    • Between 23% and 69%

      • The five-year survival rate for people with MPNST is between 23% and 69%. How long someone with MPNST lives depends on the size of the tumor and where it is in the body. People with smaller tumors tend to live longer than people whose cancer has spread to other parts of the body.
      www.cancer.gov › pediatric-adult-rare-tumor › rare-tumors
  1. Jul 31, 2024 · Factors that increase the risk of malignant peripheral nerve sheath tumors include: Radiation therapy for cancer. A malignant peripheral nerve sheath tumor might occur in the area treated with radiation 10 to 20 years after treatment. Noncancerous nerve tumors.

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  3. Jul 31, 2024 · Cai Z, et al. Prognosis and risk factors for malignant peripheral nerve sheath tumor: A systematic review and meta-analysis. World Journal of Surgical Oncology. 2020; doi:10.1186/s12957-020-02036-x. Related

  4. Jul 31, 2024 · Mayo Clinic doctors are widely respected for their expertise in diagnosing and treating rare cancers, such as malignant peripheral nerve sheath tumors. Each year, Mayo Clinic doctors care for more than 100 people with malignant nerve tumors.

  5. Jul 31, 2024 · At first glance, a malignant peripheral nerve sheath tumor (MPNST) on your arm or leg may look and feel like the sort of bump you could get by running into something or being hit. It may come as a shock to learn that bump is a rare cancerous tumor and that you’ll need surgery.

  6. Sep 30, 2020 · Malignant peripheral nerve sheath tumor (MPNST) is a rare malignant mesenchymal lesion that accounts for 5% to 10% of all soft tissue sarcoma [1, 2]. Further, 50–60% of patients with MPNST are associated to neurofibromatosis type 1 ( NF1 ); others are radiation-induced or sporadic [ 3 ].

    • Zhenyu Cai, Xiaodong Tang, Haijie Liang, Rongli Yang, Taiqiang Yan, Wei Guo
    • 2020
  7. Jan 1, 2022 · Malignant peripheral nerve sheath tumors (MPNSTs) are malignant, locally aggressive soft tissue sarcomas (STS) with nerve sheath differentiation and a high propensity to metastasize. They are rare in the general population, with an approximate lifetime incidence of 0.001% (e.g., 1/100,000) [ 1 ].

  8. Jan 27, 2014 · Prognosis is generally poor, with high rates of relapse following multimodality therapy in early disease, low response rates to cytotoxic chemotherapy in advanced disease, and propensity for rapid disease progression and high mortality.

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