2001 was the end of the 500 cc era in Grand Prix motorcycle racing; in 2002 the premier class would be renamed MotoGP and dominated by 4-stroke 990 cc machines. However, 2001 was the beginning of another era, that of Valentino Rossi 's run of championships in the top class.
The Expo 92 Grand Prix was added as a one-off race to replace the Portuguese Grand Prix which was held in Spain at the Jarama circuit. The venue hosting the Grand Prix was the Jerez circuit. The Nations Grand Prix moved from the Monza to the Imola circuit. The German Grand Prix moved from the Hockenheimring to the Nürburgring.