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An antidote is a substance that can counteract a form of poisoning. [1] The term ultimately derives from the Greek term φάρμακον ἀντίδοτον (pharmakon antidoton), " (medicine) given as a remedy". Antidotes for anticoagulants are sometimes referred to as reversal agents. [2]
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OVERVIEW. Antidotes are agents that counteract the effects of a toxic agent on the body. They do not primarily affect the systemic absorption or removal of toxic agents from the body (i.e. decontamination and enhanced elimination respectively) Antidotes have a surprisingly minor role in the management of most poisonings, their use is restricted ...
- www.ncbi.nlm.nih.gov
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Antidotes are agents that negate the effect of a poison or toxin. Antidotes mediate its effect either by preventing the absorption of the toxin, by binding and neutralizing the poison, antagonizing its end-organ effect, or by inhibition of conversion of the toxin to more toxic metabolites.
Administered by mouth, intravenously, or sometimes on the skin, it may work by directly neutralizing the poison; causing an opposite effect in the body; binding to the poison to prevent its absorption, inactivate it, or keep it from fitting a receptor at its site of action; or binding to a receptor to prevent the poison’s binding there, blocking...
