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    R1997 · Action & Adventure · 1h 45m

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  1. Nov 28, 2023 · The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance of matches. BLAST can be used to infer functional and evolutionary relationships between sequences as well as help identify ...

  2. PSI-BLAST allows the user to build a PSSM (position-specific scoring matrix) using the results of the first BlastP run. PHI-BLAST performs the search but limits alignments to those that match a pattern in the query. DELTA-BLAST constructs a PSSM using the results of a Conserved Domain Database search and searches a sequence database.

  3. BLAST, which The New York Times called the Google of biological research, [3] is one of the most widely used bioinformatics programs for sequence searching. [4] It addresses a fundamental problem in bioinformatics research. The heuristic algorithm it uses is much faster than other approaches, such as calculating an optimal alignment.

    • 2.13.0+, / 17 March 2022; 18 months ago
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  5. Mar 21, 2024 · The Basic Local Alignment Search Tool (BLAST) finds regions of similarity between sequences. The program compares nucleotide or protein sequences and calculates the statistical significance of matches. BLAST can be used to infer functional and evolutionary relationships between sequences as well as help identify members of gene families.

    • Elliott Smith
    • 2015
  6. BLAST is an acronym for Basic Local Alignment Search Tool and refers to a suite of programs used to generate alignments between a nucleotide or protein sequence, referred to as a “query” and nucleotide or protein sequences within a database, referred to as “subject” sequences. The original BLAST program used a protein “query ...

  7. Today, one of the most common tools used to examine DNA and protein sequences is the Basic Local Alignment Search Tool, also known as BLAST (Altschul et al ., 1990). BLAST is a computer algorithm ...

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