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  2. 3 days ago · Sepsis is triggered by a systemic infection and is a life-threatening, dysregulated response to infection. 1 Immune abnormalities induced by invading pathogens or tissue damage produce both the inflammatory and immunosuppressive features of the disease, which causes organ dysfunction and can lead to death. Sepsis may lead to cellular ...

  3. 2 days ago · The two studies which included patients with infection without describing subgroups of patients with sepsis and septic shock, were considered to be at a high risk of bias in the ...

  4. 4 days ago · Defining Sepsis. Sepsis is an inflammatory injury to the body resulting from the host immune response to an infectious stimulus. Sepsis results in the hospitalization of more than 700,000 people each year in the United States, with an associated mortality rate of ~20%. [6] When an expert consensus panel created a clinically applicable ...

  5. 11 hours ago · If sepsis is not treated early, it can turn into septic shock and cause the body’s organs to fail. People may need additional support in intensive care units – a ventilator to help them ...

  6. 4 days ago · The task force defined septic shock as a subset of sepsis with greater mortality risk than with sepsis alone because of particularly severe circulatory, cellular, and metabolic abnormalities. Clinical criteria for septic shock are the need for a vasopressor to maintain mean arterial pressure of 65 mm Hg or greater and a serum lactate level of ...

    • Freelance writer, Medscape
  7. 4 days ago · Background Sepsis is an infection-related systemic inflammatory response that often leads to elevated lactate levels. Monitoring lactate levels during severe sepsis is vital for influencing clinical outcomes. The aim of this study was to assess the association between plasma lactate levels and mortality in children with severe sepsis or septic shock. Methods The current prospective study was ...

  8. 5 days ago · Sepsis. Sepsis is a severe illness characterized by a systemic, whole-body response to infection and is a frequent cause of morbidity and mortality in hospitalized patients. Sepsis is most common in older individuals and infants, and can be difficult to diagnose due to its variable presentation. Because there is no confirmatory diagnostic test ...

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