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- Season 6 overviewNov 11, 2020-May 26, 202116 episodesSeason 6 episodes16. I Will Come to Save You May 26, 2021
- Choi and Archer are in hot water with an old patient; Carol receives a second chance at life.
- 15. Stories, Secrets, Half-Truths and Lies May 19, 2021
- Marcel worries he made a surgical error when a transplant patient comes in with complications.
- 14. A Red Pill, a Blue Pill May 12, 2021
- New med students begin their rotation in the ED, and Maggie keeps a careful eye on one of them.
- 13. What a Tangled Web We Weave May 5, 2021
- An auto accident sends Goodwin into a spiral as she tries to help a young boy and his mother.
- 12. Some Things Are Worth the Risk Apr 21, 2021
- Archer and Choi respond to a scene that brings back some bad memories.
- 11. Letting Go Only to Come Together Apr 7, 2021
- Choi teams up to treat a famous tennis player who is afraid his career might be over.
- 10. So Many Things We've Kept Buried Mar 31, 2021
- Marcel deals with a patient who ends up having more in common with him than he thinks.
- 9. For the Want of a Nail Mar 17, 2021
- As Manning deals with her own trauma, she steps in to help a mother in need; Dean stirs the pot.
- 8. Fathers and Mothers, Daughters and Sons Mar 10, 2021
- Choi hires an old Navy colleague to join him in the ED; Charles faces a final custody hearing.
- 7. Better Is the Enemy of Good Feb 17, 2021
- Halstead runs into trouble when one of his trial patients falls ill.
- 6. Don't Want to Face This Now Feb 10, 2021
- Choi helps a patient with chronic pain find a solution; Halstead considers a new path.
- 5. When Your Heart Rules Your Head Feb 3, 2021
- Dr. Halstead finds success in his trial; Dr. Charles' daughter receives life-changing news.
- 4. In Search of Forgiveness, Not Permission Jan 27, 2021
- Dr. Marcel and Dr. Manning lay everything on the line to assist a sick woman.
- 3. Do You Know the Way Home? Jan 13, 2021
- Dr. Charles and April team up to take on a mysterious patient in the ED.
- 2. Those Things Hidden in Plain Sight Nov 18, 2020
- Goodwin announces a new ED Chief; Dr. Manning takes a stand for a patient.
- 1. When Did We Begin to Change Nov 11, 2020
- The staff adjusts to the pandemic; Dr. Halstead and Hannah face a troubling reality.