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5 days ago · As the spike protein is an envelope protein, ... Lu, J. et al. A COVID-19 mRNA vaccine encoding SARS-CoV-2 virus-like particles induces a strong antiviral-like immune response in mice.
5 days ago · The SARS-related coronavirus is an enveloped, positive-sense, single-stranded RNA virus. Its genome is about 30 kb, which is one of the largest among RNA viruses. The virus has 14 open reading frames which overlap in some cases. [18] The genome has the usual 5′ methylated cap and a 3′ polyadenylated tail. [19]
3 days ago · The protein of interest is the spike protein, a protein on the exterior of the virus that enables SARS-type coronaviruses to enter cells through the ACE2 receptor. Following vaccination, the production of coronavirus spike protein within the body will cause the immune system to attack the spike protein with antibodies and T-cells if the virus ...
- AU: B1
- SARS-CoV-2
- Vaxzevria, Covishield
- Viral vector
5 days ago · The history of coronaviruses is an account of the discovery of the diseases caused by coronaviruses and the diseases they cause. It starts with the first report of a new type of upper-respiratory tract disease among chickens in North Dakota, U.S., in 1931. The causative agent was identified as a virus in 1933.
2 days ago · COVAX delivered around 850 million COVID-19 vaccine doses in 2022. Complete primary series coverage reached 53% across AMC countries in December 2022, up from 31% in December 2021. With targeted support, the number of AMC countries below 10% full coverage dropped from 34 to 7 during the same period.
3 days ago · SARS-CoV-2 is a positive-sense single-stranded RNA virus. It is contagious in humans and is the cause of the coronavirus disease 2019 (COVID-19). Latest Research and Reviews. High SARS-CoV-2...
4 days ago · Definition. A virus is an infectious microbe consisting of a segment of nucleic acid (either DNA or RNA) surrounded by a protein coat. A virus cannot replicate alone; instead, it must infect cells and use components of the host cell to make copies of itself. Often, a virus ends up killing the host cell in the process, causing damage to the host ...
