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  1. A Mississippi River cruise offers the rare opportunity to sail through America's heartland on the world’s #1 river cruise line. Explore picturesque towns and boom cities; take in views of pastoral farms and towering bluffs; and immerse yourself in the region's rich history and culture with an included excursion in every port.

  2. Apr 5, 2024 · American Cruise Lines offers the 23-day Complete Mississippi Cruise in 2024, 2025 and 2026, with sailings available on three 180-passenger modern river ships: American Melody, American Serenade and American Symphony. After a pre-cruise hotel stay in New Orleans, passengers journey through all aspects of American history.

  3. History and culture unfold as you traverse the Mississippi on this enriching voyage. Enjoy relaxing scenic sailing and unparalleled bird-watching as the landscape changes between the bluffs of the North and the bayous of the South. Learn about the American civil rights movement and the Civil War. Along the way, tap your feet to the rhythm of American folk, soul and jazz music—and taste a ...

  4. Pre-Cruise Four Seasons St. Louis Pre-Cruise Package. Day 1 St. Louis, MO/Alton, IL. Day 2 Cruising the Mississippi River. Day 3 Hannibal, MO. Day 4 Day of Cruising. Day 5 Muscatine, IA. Day 6 Dubuque, IA. Day 7 Winona, MN. Day 8 Red Wing, MN.

  5. Call 1.406.541.2677. Start Planning My Trip. Taking a cruise on the mighty Mississippi River is a journey into the heart and soul of America. The Mississippi is known for being one of the longest rivers in the world, starting in Northern Minnesota and flowing down to the Gulf of Mexico. Through carefully planned urban explorations and village ...

  6. The Riverboat Twilight. Since 1985, the Riverboat Twilight has delivered one of the most exceptional cruise experiences in the Midwest. And it’s not just a cruise; it’s a conduit to reconnection, relaxation, and renewal. Marvel at the majestic Mississippi river while relaxing in style aboard a stunningly replicated Victorian Riverboat.

  7. The Best Time To Take A Mississippi River Cruise. From New Orleans to Memphis, St. Louis to St. Paul, and beyond, we offer advice on the ideal seasons to embark on a Mississippi River cruise. We have over nine unique Mississippi River cruise itineraries to choose from, and our goal is to help find the perfect time and temperature for you. Read more

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