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23 minutes ago · This reaction is done by the quinone aromatic compound in doxorubicin receiving a single electron via flavoenzymes such as NADPH-cytochrome P450 reductase and mitochondrial NADH dehydrogenase to produce semiquinone . The DOX semiquinone radical formation further reduces free oxygen into the superoxide free radicals which creates an imbalance ...
23 minutes ago · Pavez Loriè E, Li H, Vahlquist A, Törmä H (2009) The involvement of cytochrome p450 (CYP) 26 in the retinoic acid metabolism of human epidermal keratinocytes. Biochim Biophys Acta Mol Cell Biol Lipids 1791:220–228.
1 day ago · Feature papers represent the most advanced research with significant potential for high impact in the field. A Feature Paper should be a substantial original Article that involves several techniques or approaches, provides an outlook for future research directions and describes possible research applications.
23 minutes ago · The metabolites of tryptophan are ligands to an important receptor called aryl hydrocarbon receptor (part of the cytochrome P450 complex) which is involved in the metabolism and breakdown of many drugs, xenobiotics, and chemicals (Russo et al. 2019). Moreover, folates which are commonly known as vit.
1 day ago · A major metabolic catalyst involved is the cytochrome P450 enzyme known as 2D6, or CYP2D6. A significant portion of the population has a functional deficiency in this enzyme and are known as poor CYP2D6 metabolizers.
- C₁₈H₂₅NO
- Robitussin, Delsym, others
- AU: A
