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David E. Fisher is a researcher, clinician and academic, and serves as Chief of the MGH Department of Dermatology, Director of the MGH Cutaneous Biology Research Center and Director of the Melanoma Center at MGH. He is also the President of the Society for Melanoma Research, the largest international society dedicated to the study of melanoma.
About David Fisher, MD, PhD. David E. Fisher, MD, PhD is an internationally known researcher, clinician and academic, who is Chief of the Massachusetts General Hospital Department of Dermatology at Harvard Medical School in Boston, Massachusetts (USA). He also serves as Director of the MGH Cutaneous Biology Research Center and Director of the ...
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David E. Fisher. Edward Wigglesworth Professor of Dermatology. Our group studies cell death/proliferation signals in relation to development and disease, particularly in skin cancer. We attempt to understand critical modes of cell homeostasis with a goal of molecular targeted therapy as well as prevention of melanoma and other human cancers.
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- Lessons For Malignancy from Normal Development
- Control of Life and Death in Melanoma
- Mitf Transcription Factor Family in Development and Cancer
The Laboratory of David Fisher, MD, PhD, at Massachusetts General Hospital studies the biology of melanocytes as a means of identifying pathways that drive melanoma in man. This includes examination of mechanisms underlying growth/survival of benign moles, most of which contain mutations in either BRAF or N-Ras oncogenes. We also study melanocyte d...
Malignant transformation of melanocytes produces one of the most treatment resistant malignancies in man. We have identified a transcriptional network that regulates melanoma cell survival and proliferation as well as melanocyte differentiation during development. Using diverse methods including mouse models, human tumor expression arrays and cellu...
MITF is a helix-loop-helix factor homologous to Myc, whose mutation in man produces absence of melanocytes. MITF acts as a master regulator of melanocyte development and is targeted by several critical signaling pathways. Recently, members of the MITF family have been discovered as oncogenes in a variety of human malignancies, particularly sarcomas...
A world-renowned scientist, clinician and educator, David Fisher, MD, PhD, is chief of the Dermatology Service at Mass General and director of the Dr. Fisher's laboratory studies the basic science of skin pigmentation and examines the molecular and genetic events that lead to melanoma, the deadliest form…
About The Provider. David E. Fisher, MD, PhD is an internationally known researcher, clinician and academic, who is Chief of the Massachusetts General Hospital Department of Dermatology at Harvard Medical School in Boston, Massachusetts (USA). He also serves as Director of the MGH Cutaneous Biology Research Center and Director of the Melanoma ...
David E. Fisher. Edward Wigglesworth Professor of Dermatology. Our group studies cell death/proliferation signals in relation to development and disease, particularly in skin cancer. We attempt to understand critical modes of cell homeostasis with a goal of molecular targeted therapy as well as prevention of melanoma and other human cancers.
