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  1. Sep 6, 2024 · While encouraging, additional data from well-conducted randomized trials in patients with sepsis are required before we can routinely recommend procalcitonin use all patients with sepsis. Detailed evidence to support the use of procalcitonin is provided separately.

  2. 1 day ago · Sepsis is a critical condition that significantly burdens healthcare systems globally. Given the heterogeneity among sepsis patients, identifying high-risk mortality groups is crucial [ 1 ]. Procalcitonin (PCT) is a well-established biomarker for evaluating sepsis severity and guiding antibiotic therapy [ 2 ].

  3. Sep 9, 2024 · Sepsis is a life-threatening condition caused by the body’s response to an infection. This article explores the role of assessment tools in sepsis identification, as well as the Sepsis Six strategy, which is used to treat the condition. One Sepsis Six intervention is the use of antibiotics; when used unnecessarily, these can contribute to ...

  4. 2 days ago · Procalcitonin (PCT) is an acute phase reactant that is used as a biomarker for the diagnosis of sepsis and as a guide for antibiotic stewardship. Refer to the Monitoring section below. C-Reactive Protein. C-reactive protein (CRP) is a nonspecific marker of acute inflammation.

  5. 1 day ago · Westwood M, Ramaekers B, Whiting P, et al. Procalcitonin testing to guide antibiotic therapy for the treatment of sepsis in intensive care settings and for suspected bacterial infection in emergency department settings: a systematic review and cost-effectiveness analysis.

    • Do we need procalcitonin for sepsis?1
    • Do we need procalcitonin for sepsis?2
    • Do we need procalcitonin for sepsis?3
    • Do we need procalcitonin for sepsis?4
  6. Sep 2, 2024 · Remarkably, procalcitonin and C-reactive protein were equally helpful in lowering the requirement for antibiotics in sepsis patients undergoing medical care, according to research done by Oliveira et al. in 2013 .

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  8. 1 day ago · The 2021 American Academy of Pediatrics Clinical Practice Guideline (CPG) for evaluation of well-appearing febrile infants 8 to 60 days of age strongly recommends the use of inflammatory markers (IMs), including procalcitonin (PCT), to inform decision-making.1,2 Given PCT has better diagnostic accuracy for detecting a bacterial infection than other IMs,3 the recommended practice change can ...

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