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Sep 6, 2024 · While encouraging, additional data from well-conducted randomized trials in patients with sepsis are required before we can routinely recommend procalcitonin use all patients with sepsis. Detailed evidence to support the use of procalcitonin is provided separately.
- Evans L, Rhodes A, Alhazzani W, Et Al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021. Crit Care Med 2021; 49:E1063
Surviving Sepsis Campaign: International Guidelines for...
- Gregory a Schmidt, MD
UpToDate, electronic clinical resource tool for physicians...
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- Howell Md, Davis Am. Management of Sepsis and Septic Shock. JAMA 2017; 317:847
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- Gaieski Df, Mikkelsen Me, Band Ra, Et Al. Impact of Time to Antibiotics on Survival in Patients With Severe Sepsis Or Septic Shock in Whom Early Goal-Directed Therapy Was Initiated in The Emergency Department. Crit Care Med 2010; 38:1045
RATIONALE Patients with severe sepsis without shock or...
- Carson Jl, Grossman Bj, Kleinman S, Et Al. Red Blood Cell Transfusion: a Clinical Practice Guideline From The Aabb*. Ann Intern Med 2012; 157:49
METHODS We retrospectively reviewed the medical records of...
- National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (Ards) Clinical Trials Network, Wheeler Ap, Bernard Gr, Et Al. Pulmonary-artery Versus Central Venous Catheter to Guide Treatment of Acute Lung Injury. N Engl J Med 2006; 354:2213
Medline ® Abstract for Reference 81 of 'Evaluation and...
- Hollenberg Sm, Ahrens Ts, Annane D, Et Al. Practice Parameters for Hemodynamic Support of Sepsis in Adult Patients: 2004 Update. Crit Care Med 2004; 32:1928
Medline ® Abstract for Reference 130 of 'Evaluation and...
- Evans L, Rhodes A, Alhazzani W, Et Al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021. Crit Care Med 2021; 49:E1063
1 day ago · Sepsis is a critical condition that significantly burdens healthcare systems globally. Given the heterogeneity among sepsis patients, identifying high-risk mortality groups is crucial [ 1 ]. Procalcitonin (PCT) is a well-established biomarker for evaluating sepsis severity and guiding antibiotic therapy [ 2 ].
Sep 9, 2024 · Sepsis is a life-threatening condition caused by the body’s response to an infection. This article explores the role of assessment tools in sepsis identification, as well as the Sepsis Six strategy, which is used to treat the condition. One Sepsis Six intervention is the use of antibiotics; when used unnecessarily, these can contribute to ...
2 days ago · Procalcitonin (PCT) is an acute phase reactant that is used as a biomarker for the diagnosis of sepsis and as a guide for antibiotic stewardship. Refer to the Monitoring section below. C-Reactive Protein. C-reactive protein (CRP) is a nonspecific marker of acute inflammation.
1 day ago · Westwood M, Ramaekers B, Whiting P, et al. Procalcitonin testing to guide antibiotic therapy for the treatment of sepsis in intensive care settings and for suspected bacterial infection in emergency department settings: a systematic review and cost-effectiveness analysis.
Sep 2, 2024 · Remarkably, procalcitonin and C-reactive protein were equally helpful in lowering the requirement for antibiotics in sepsis patients undergoing medical care, according to research done by Oliveira et al. in 2013 .
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1 day ago · The 2021 American Academy of Pediatrics Clinical Practice Guideline (CPG) for evaluation of well-appearing febrile infants 8 to 60 days of age strongly recommends the use of inflammatory markers (IMs), including procalcitonin (PCT), to inform decision-making.1,2 Given PCT has better diagnostic accuracy for detecting a bacterial infection than other IMs,3 the recommended practice change can ...