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Sep 1, 2022 · View Gokul Kesavan’s profile on LinkedIn, a professional community of 1 billion members. Chief Scientific Officer at Vowels LifeSciences Private Limited · Experienced and innovative research...
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- Vowels LifeSciences Private Limited
- Bangalore Urban, Karnataka, India
Dr. Gokul Kesavan has over 18 years of research experience from cutting-edge research institutes like the Center for Regenerative Therapies Dresden, Germany (Postdoc, 2011-2019) and the Stem cell Center Lund University, Sweden (Ph.D., 2003-2009).
Together, data from gain- and loss-of-function experiments suggest that zebrafish Ism1 plays a complex role in regulating extracellular signals during early embryonic development. Keywords: FCS; Fgf signaling; Isthmin1; Isthmin2; Nodal signaling; Secreted factors; Zebrafish.
- Gokul Kesavan, Florian Raible, Florian Raible, Mansi Gupta, Anja Machate, Dilara Yilmaz, Dilara Yilm...
- 2021
This mini-review assesses the status of CRISPR-based therapies, both in vivo and ex vivo, and the challenges associated with clinical translation. In vivo CRISPR therapies have been used to treat eye and liver diseases due to the practicality of delivering editing components to the target tissue.
Feb 18, 2021 · Kesavan G, Hammer J, Hans S, Brand M. Targeted knock-in of CreERT2in zebrafish using CRISPR/Cas9. Cell Tissue Res. 2018; 372:41–50. doi: 10.1007/s00441-018-2798-x. [Google Scholar]
- Stefan Hans, Daniela Zöller, Juliane Hammer, Johanna Stucke, Sandra Spieß, Gokul Kesavan, Volker Kro...
- 10.1038/s41467-021-21427-6
- 2021
- Nat Commun. 2021; 12: 1125.
Gokul KESAVAN | Cited by 617 | of Technische Universität Dresden, Dresden (TUD) | Read 29 publications | Contact Gokul KESAVAN.
The Cre-loxp recombination system is widely used to activate or inactivate genes with high spatial and temporal specificity. Using a CRISPR/Cas9-mediated knock-in strategy, we inserted a zebrafish codon-optimized CreER T2 transgene at the otx2 gene locus to generate a conditional Cre-driver line.
