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May 1, 2024 · Background The increasing burden of dengue virus on public health due to more explosive and frequent outbreaks highlights the need for improved surveillance and control. Genomic surveillance of dengue virus not only provides important insights into the emergence and spread of genetically diverse serotypes and genotypes, but it is also critical to monitor the effectiveness of newly implemented ...
Apr 25, 2024 · Hanley et al show that transmission of dengue and Zika virus from Old and New World monkeys is shaped by an immunologically-mediated trade-off between magnitude and duration of replication.
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May 14, 2024 · It results in virus inactivation such that the virus is no longer able to infect and replicate in cell culture. PRNT can detect and measure the titer of specific neutralizing antibodies against dengue virus and other flaviviruses from the serum of an infected patient.
5 days ago · Dengue virus (DV), a member of the Flaviviridae family, has been demonstrated to induce changes to the actin cytoskeleton to promote efficient viral entry and replication. These cytoskeletal alterations continue throughout infection, and disruption of the cytoskeleton has been shown to decrease the release of infectious virions. However, few studies have assessed the contribution of actin ...
May 4, 2024 · Dengue virus (DENV) is a continuing global threat that puts half of the world’s population at risk for infection. This mosquito-transmitted virus is endemic in over 100 countries. When a mosquito takes a bloodmeal, virus is deposited into the epidermal and dermal layers of human skin, infecting a variety of permissive cells, including keratinocytes, Langerhans cells, macrophages, dermal ...
May 14, 2024 · A nucleic acid amplification test (NAAT) (e.g., RT-PCR) and an IgM antibody test OR. A NS1 antigen test and an IgM detection test. A serum sample is preferred for dengue testing. Dengue virus RNA can be detected with NAAT in blood, serum, and plasma. Most of these tests identify the infecting dengue virus serotype.
Apr 25, 2024 · Dengue is an acute febrile illness viral infection caused by dengue virus (DENV), which is transmitted to humans through the bite of an infected Aedes mosquito 1,2,3.There are four genetically ...
