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4 days ago · Dengue virus (DV), a member of the Flaviviridae family, has been demonstrated to induce changes to the actin cytoskeleton to promote efficient viral entry and replication. These cytoskeletal alterations continue throughout infection, and disruption of the cytoskeleton has been shown to decrease the release of infectious virions. However, few studies have assessed the contribution of actin ...
1 day ago · Author summary This study, conducted from 2012 to 2022, aimed at understanding the dynamics and genetic diversity of dengue virus on Reunion Island, a French overseas department located in the southwestern Indian Ocean, which is regularly affected by dengue epidemics. Several thousand clinical isolates and patient samples were collected from across the island and sequenced, resulting in 877 ...
5 days ago · Role of angiotensin II in dengue virus replication. Once inside the cell, DENV replicates, activating several mechanisms. One of the best-studied mechanisms of DENV entry is clathrin-mediated endocytosis. DENV becomes enclosed in a vesicle covered with clathrin in the cytoplasm [8, 10]. The clathrin then disassembles, and the virus is ...
1 day ago · Dengue is a viral infection caused by the dengue virus (DENV), spread through the bite of an infected mosquito. Most cases are caused by the Aedes aegypti mosquito, but other types of mosquitos can also transmit dengue. In 2019, 5.2M cases of dengue infections were reported worldwide. This increased from over 500 thousand cases in 2000.
5 days ago · Dengue is a mosquito-borne viral disease caused by the dengue virus, an Arbovirus (arthropod-borne virus). Also known as break bone fever, a severe form of dengue is called dengue hemorrhagic fever (DHF). The disease is transmitted via the bite of an infected female Aedes aegypti mosquito.
4 days ago · Background: C-type lectins play a crucial role as pathogen-recognition receptors for the dengue virus, which is responsible for causing both dengue fever (DF) and dengue hemorrhagic fever (DHF).
4 days ago · Background: C-type lectins play a crucial role as pathogen-recognition receptors for the dengue virus, which is responsible for causing both dengue fever (DF) and dengue hemorrhagic fever (DHF). DHF is a serious illness caused by the dengue virus, which exists in four different serotypes: DEN-1, DEN-2, DEN-3, and DEN-4. We conducted a genetic association study, during a significant DEN-2 ...
