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  1. May 13, 2022 · Paxlovid has been found to be about 88% effective in preventing hospitalization and death in unvaccinated, high-risk adults with COVID-19.

  2. Apr 15, 2024 · Studies have shown Paxlovid to reduce hospitalization and death by 86% in unvaccinated COVID patients (in initial trials by Pfizer, which developed the drug), and 80% effective in those who have been vaccinated.

  3. Nov 15, 2023 · Official answer. by Drugs.com. Paxlovid lowers the risk of hospitalization or death from COVID-19 by 86% for adult patients who are at high risk of COVID-19 progressing to severe illness when Paxlovid is started within the first 3 days of COVID-19 symptoms.

  4. The US Food and Drug Administration (FDA) approved Paxlovid last May for the treatment of mild to moderate COVID-19 in adults who are at risk of progression to severe disease. But it has been available since early 2022 under Emergency Use Authorization (EUA) from the FDA for treating COVID-19 in people 12 years or older.

  5. Paxlovid has not been approved but has been authorized for emergency use by FDA under an EUA, for the treatment of mild to moderate COVID-19 in adults who are at high-risk for progression to severe COVID-19, including hospitalization or death.

  6. The COVID-19 Treatment Guidelines Panel (the Panel) recommends using nirmatrelvir 300 mg with ritonavir 100 mg (Paxlovid) orally (PO) twice daily for 5 days in nonhospitalized adults with mild to moderate COVID-19 who are at high risk of disease progression ( AIIa. ).

  7. Jan 10, 2023 · In 2021, a clinical trial found that a combination of the antiviral drugs nirmatrelvir and ritonavir reduced the risk of severe COVID-19 by almost 90% for unvaccinated people. The combination is sold under the name Paxlovid. Today, most of the U.S. population is vaccinated against SARS-CoV-2.

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