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Influenza A virus subtype H2N2 (A/H2N2) is a subtype of Influenza A virus. H2N2 has mutated into various strains including the "Asian flu" strain (now extinct in the wild), H3N2, and various strains found in birds. It is also suspected of causing a human pandemic in 1889.
Mar 30, 2023 · Current subtypes of influenza A viruses that routinely circulate in people include A(H1N1) and A(H3N2). Influenza A subtypes can be further broken down into different genetic “clades” and “sub-clades.” See the “Influenza Viruses” graphic below for a visual depiction of these classifications.
Sep 17, 2021 · The H2N2 subtype of influenza A virus which emerged in the Hunan Province of China in February 1957, was believed to be clinically milder than the H1N1 virus that caused the 1918 pandemic with a mortality rate worldwide of 1.1 million deaths . The virus circulated globally until H3N2 appeared in 1968, causing another pandemic.
- Rina Fajri Nuwarda, Abdulsalam Abdullah Alharbi, Veysel Kayser
- 10.3390/vaccines9091032
- 2021
- Vaccines (Basel). 2021 Sep; 9(9): 1032.
The 1957 flu outbreak caused an estimated one million to two million deaths worldwide and is generally considered to have been the least severe of the three influenza pandemics of the 20th century. The 1957 outbreak was caused by a virus known as influenza A subtype H2N2.
- Kara Rogers
Apr 4, 2019 · Influenza A viruses of the H2N2 subtype initiated a pandemic in 1957, causing morbidity and mortality in humans, an event also known as the “Asian flu pandemic” ( 1, – 3 ). No surveillance systems were in place in 1957 to accurately detect and record the A/H2N2 pandemic outbreak scenario.
- M. Linster, M. Linster, E. J. A. Schrauwen, S. van der Vliet, D. F. Burke, P. Lexmond, T. M. Bestebr...
- 2019
Influenza A viruses naturally infect humans, causing epidemics and pandemics of respiratory disease. Influenza A viruses of the H1N1, H1N2, and H3N2 subtypes are currently circulating among humans while H2N2 viruses circulated among humans in the mid-1900s.
Feb 2, 2015 · The 1957 A/H2N2 influenza virus caused an estimated 2 million fatalities during the pandemic. Since viruses of the H2 subtype continue to infect avian species and pigs, the threat of reintroduction into humans remains.
