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4 days ago · Obligate intracellular, small Gram-negative coccobacillus [ Fig 1 ], member of Rickettsiaceae family, the agent of Rocky Mountain spotted fever (RMSF). Tick-transmitted, it occurs most commonly in late spring to early fall but may occur year-round in warmer states (e.g., the Southeastern U.S.). The common American brown dog tick is the most ...
5 days ago · Stamford resident K.J. Kelly didn't know about Rocky Mountain spotted fever (RMSF) until he was admitted to Stamford Health's emergency department. What he originally thought was the flu turned ...
4 days ago · Some arthropod-borne obligate intracellular rickettsiae are among the most virulent human pathogens. Upon entry, Rickettsia species modulate immune (e.g., macrophages; MΦ) and non-immune cell (e.g., endothelial cells) responses to create a habitable environment for host colonization. In particular, MΦ play a crucial role in either terminating an infection at an early stage or succumbing to ...
1 day ago · Listeria monocytogenes is an anaerobic and gram-positive bacillus found commonly in animal and human feces and in the soil and thus also in food and water 5. In most cases, the bacteria is injested orally and reaches the enteric nerves through a breach in the mucosa or via dental disease and becomes an intracellular pathogen 5,6.
6 days ago · Rocky mountain spotted fever is a severe disease caused by Rickettsia rickettsii that frequently causes the death of the patients. As there are not effective vaccines for this disease, we employed reverse vaccinology to find epitope candidates useful for vaccine development.
3 days ago · Local Case Brings Awareness to Tick-Borne Illness by Stamford Health – Rocky Mountain spotted fever is caused by the tick-borne bacteria Rickettsia rickettsii. It has spread across the US to areas where it was not previously found, as one man from Connecticut learned when he felt flu-like with a high fever.
3 hours ago · The World Health Organization (WHO) claims that drinking water contaminated with pathogens, like protozoa, bacteria, prions, viruses, rickettsia, and fungi, is the primary cause of 80% of diseases in developing nations, posing a serious threat to human health and claiming millions of lives annually all over the world (Chi Zhang et al. 2018).
