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  1. Jul 01, 2014 · Thus, there is an unmet need for the development of a consensus definition for sepsis in both preterm and term neonates to be used for future clinical studies. The pediatric consensus definition of sepsis is SIRS in the presence of or as a result of suspected or proven infection.

  2. Jan 11, 2022 · Neonates, particularly preterm neonates, rarely manifest fever greater than 38°C even with sepsis and septic shock and are more likely to manifest temperature instability or hypothermia.

  3. Because there is no consensus definition for neonatal sepsis, 11 we considered a new bacteremic or fungemic event in an infant aged greater than 72 hours who received 5 or more days of antibiotic ...

  4. There is currently no consensus definition of neonatal sepsis and the definitions that are currently in use are varied. A consensus definition of neonatal sepsis would benefit clinicians, patients ...

  5. Unless there is a strong clinical or biochemical indication to prolong antibiotics physician need to trust the culture results and to stop antibiotics for suspected sepsis within 36-48 h. Secondly, an international robust and pragmatic neonatal sepsis definition is urgently needed. Neonatal sepsis is a dynamic condition.

  6. Jan 07, 2022 · A wide variation of outcomes reported among published RCTs on the management of neonatal sepsis is identified and the paucity of standardised outcome reporting hinders comparison and synthesis of data. Background The lack of a consensus definition of neonatal sepsis and a core outcome set (COS) proves a substantial impediment to research that influences policy and practice relevant to key ...

  7. Nov 20, 2021 · Is there truly a need for an international consensus-based definition of neonatal sepsis to inform all future trials—or is there actually a need for the neonatal research community to step back ...

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