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  1. Jan 22, 2021 · Applied sepsis definitions are mostly adaptations of the clinical consensus criteria, 9 such as when laboratory testing was unavailable, 31 or relied on selected clinical symptoms of neonatal sepsis. Currently, there is no sepsis definition for the neonatal age group in line with the current sepsis definition, 48 which can be applied in all ...

  2. Mar 19, 2020 · Cardiovascular dysfunction is common in neonatal sepsis but there is no consensus-based definition, making calculating the incidence and designing clinical trials challenging, and future developments in neonats management will be facilitated by common definitions and datasets especially in Neonatal cardiovascular optimisation.

  3. Jun 12, 2020 · Neonatal sepsis defines the systemic condition that arises from the bacterial, viral or fungal origin, associated with hemodynamic changes and clinical findings and causing severe morbidity and mortality. Its incidence varies depending on the definition of the case and the population studied and is between 1 and 5 in 1000 live births.

  4. Prior to 2005, there was not a standard definition for pediatric sepsis which resulted in a lack of uniformity among sepsis studies. In 2005, the Pediatric Sepsis Consensus Congress (PSCC) met to standardize the definition of sepsis ( Figure 1 ); however, as seen with adults, the definition requires continuous reconsideration and modification ...

  5. Sep 13, 2017 · There is currently no consensus definition of neonatal sepsis and the definitions that are currently in use are varied. A consensus definition of neonatal sepsis would benefit clinicians, patients ...

  6. Method A systematic search of the Embase and Cochrane databases was performed for RCTs which explicitly stated a definition for neonatal sepsis. Definitions were sub-divided into five primary criteria for infection (culture, laboratory findings, clinical signs, radiological evidence and risk factors) and stratified by qualifiers (early/late ...

  7. Impact: There is currently no consensus definition of neonatal sepsis and the definitions that are currently in use are varied.A consensus definition of neonatal sepsis would benefit clinicians, patients and researchers.Recent progress in adults with publication of Sepsis-3 provides guidance on how a consensus definition and screening criteria ...

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