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  1. Toshiaki KAWACHI | Cited by 1,048 | of Gifu University, Gifu-shi (Gidai) | Read 28 publications | Contact Toshiaki KAWACHI

    • Abstract
    • Materials and Methods
    • Results
    • Discussion
    • Acknowledgments

    The branched-chain amino acids (BCAAs) leucine, isoleucine, and valine are essential amino acids. BCAAs can be oxidized in skeletal muscle, whereas other essential amino acids are catabolized mainly in the liver (1). Skeletal muscle is the main target of glucose use and insulin activity, which causes protein anabolism (2). Glucose is taken from nut...

    The Takayama Study

    Subjects in this study were cohort members from a population-based cohort study conducted in Takayama City, Gifu Prefecture, Japan. The Takayama Study was initiated in 1992 to identify dietary and lifestyle factors in relation to morbidity from chronic diseases. A total of 31,552 Takayama residents aged 35 years or more completed a self-administered baseline questionnaire which included questions on demographic characteristics, smoking, diet, physical activity, and medical and reproductive hi...

    Follow-up and endpoints

    Subjects for the present follow-up study were restricted to those who were less than 70 years of age at baseline (n = 26,546). In July 2002, a follow-up questionnaire seeking information about diabetes was sent to these persons. Deaths and moves in this cohort were certified by means of the residential registry. After exclusion of persons who were deceased (n = 1,505), were physically unable to complete the questionnaire (n = 51), or had moved (n = 2,598), the study population consisted of 22...

    Statistical analysis

    Total BCAA intake (sum of leucine, isoleucine, and valine intakes) and total protein intake were highly correlated. Therefore, total BCAA intake was expressed as a percentage of total protein intake based on the report by Qin et al. (23). Subjects were divided into 3 equal groups according to tertile of total BCAA intake. Since 30 men and 10 women who developed diabetes during the follow-up period did not provide information regarding the time of diagnosis, we assigned median values for time...

    Characteristics of the study population, by sex and tertile of total BCAA intake (percentage of total protein intake), are shown in Table 1. Men and women who had a greater intake of total BCAAs were more likely to be older and less educated (<15 years) and to have reported a history of hypertension. They also had lower intakes of dietary fiber, al...

    In the present prospective study, high intakes of total BCAAs, leucine, and valine were associated with a decreased risk of diabetes in women. In men, leucine intake was marginally significantly inversely associated with the risk of diabetes. Our results suggest a beneficial effect of dietary leucine or BCAAs in preventing diabetes. However, at pre...

    Author affiliations: Department of Epidemiology and Preventive Medicine, Graduate School of Medicine, Gifu University, Gifu, Japan (Chisato Nagata, Kozue Nakamura, Keiko Wada, Michiko Tsuji, Yuya Tamai, and Toshiaki Kawachi). This study was supported by grants from the Japanese Ministry of Health, Labour and Welfare and the Ministry of Education, C...

    • Chisato Nagata, Kozue Nakamura, Keiko Wada, Michiko Tsuji, Yuya Tamai, Toshiaki Kawachi
    • 2013
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  4. Kawachi Toshiaki. Producer. IMDbPro Starmeter See rank. Kawachi Toshiaki is known for Moumantai (1999). Add photos, demo reels. Add to list. More at IMDbPro. Contact info. Agent info. Known for: Moumantai. 5.0. Producer. 1999. Credits. IMDbPro. Producer. Previous. 1. Moumantai. 5.0. producer. 1999. Contribute to this page.

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  6. Consumption of coffee, green tea, oolong tea, black tea, chocolate snacks and the caffeine content in relation to risk of diabetes in Japanese men and women Volume 103, Issue 3 Shino Oba (a1) , Chisato Nagata (a1) , Kozue Nakamura (a1) , Kaori Fujii (a1) , Toshiaki Kawachi (a1) , Naoyoshi Takatsuka (a1) and Hiroyuki Shimizu (a1) (a2)

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