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  1. Michael Smith CC OBC FRS [1] (April 26, 1932 – October 4, 2000) was a British-born Canadian biochemist and businessman. He shared the 1993 Nobel Prize in Chemistry [3] with Kary Mullis for his work in developing site-directed mutagenesis. Following a PhD in 1956 from the University of Manchester, [4] he undertook postdoctoral research with ...

  2. Apr 22, 2024 · Michael Smith (born April 26, 1932, Blackpool, England—died October 4, 2000, Vancouver, British Columbia, Canada) was a British-born Canadian biochemist who won (with Kary B. Mullis) the 1993 Nobel Prize for Chemistry for his development of a technique called oligonucleotide-based site-directed mutagenesis. This technique enabled researchers ...

    • The Editors of Encyclopaedia Britannica
  3. Michael Smith was a British-born Canadian biochemist who won a share of the 1993 Nobel Prize in Chemistry for his work in developing site-directed mutagenesis. His work enabled researchers to introduce specific mutations into genes and paved the way to study gene therapy approaches for cystic fibrosis, sickle-cell disease, and hemophilia, among ...

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  5. www.science.ca › scientists › scientistprofilescience.ca : Michael Smith

    The Science. Molecular biology is the study of biological systems at the level of individual chemicals and molecules. Michael Smith was an expert on the chemistry of DNA — the molecule that makes up genes, the instructions required to create every part of an organism. DNA is a large molecule that is like a twisting chain.

  6. Oct 23, 2018 · A Nobel legacy: Michael Smith was a trailblazing researcher and champion of science literacy. The symposium began with a panel presentation on Smith’s life and career. Courtesy Alexander Kim. October 1 marked 25 years since Michael Smith won the Nobel Prize in chemistry for his work at UBC. Smith, who passed away in 2000, is most well-known ...

  7. Sep 28, 2018 · Dr. Michael Smith accepting the Nobel Prize in Chemistry in 1993. In 1976, a couple of biochemists brainstormed over coffee at a University of Cambridge cafeteria. Dr. Michael Smith thought out loud, ideas sparking from his 20 years of experience studying the chemical synthesis of oligonucleotides, the elementary units of DNA and RNA.

  8. Michael Smith was a British-born Canadian biochemist and businessman. He shared the 1993 Nobel Prize in Chemistry with Kary Mullis for his work in developing site-directed mutagenesis. Following a PhD in 1956 from the University of Manchester, he undertook postdoctoral research with Har Gobind Khorana at the British Columbia Research Council in Vancouver, British Columbia, Canada. Subsequently ...

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