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NMDA receptors (NMDARs) are glutamate-gated cation channels with high calcium permeability that play important roles in many aspects of the biology of higher organisms. They are critical for the development of the central nervous system (CNS), generation of rhythms for breathing and locomotion, and the processes underlying learning, memory, and ...
NMDA receptors are one of the important glutamate receptors of the CNS, and are important in cognitive, motor, and psychiatric function. A “new” autoimmune encephalitis with autoantibodies binding to the NR1/NR2 subunits of the NMDA-R was described by Dalmau in 2007 ( Dalmau et al., 2007 ).
Mar 17, 2017 · NMDA receptors are preeminent neurotransmitter-gated channels in the CNS, which respond to glutamate in a manner that integrates multiple external and internal cues.
May 2, 2016 · NMDA receptors are ionotropic glutamate receptors that function as heterotetramers composed mainly of GluN1 and GluN2 subunits.
May 20, 2013 · NMDA receptors (NMDARs) are ion channels gated by the excitatory neurotransmitter glutamate. NMDARs are widespread in the CNS and are essential mediators of synaptic transmission and plasticity.
Aug 1, 2008 · The N-methyl-d-aspartate (NMDA) receptor is multi-subunit ligand-gated channel which is highly expressed in the mammalian and human central nervous system. Multiple subtypes of the NMDA receptor comprising distinct subunit combinations exist which subserve distinct roles in the brain and spinal cord, which offers new hope to develop, in a ...
Oct 4, 2019 · NMDA receptors are proteins that are embedded in the membrane of post-synaptic neurons. The N-methyl-D-aspartate (NMDA) receptors are made up of five subunits that have a similar amino acid sequence to other glutamate membrane receptor classes such as the AMPA (α-amino-3-hydroxy-5-methly-4-isoxazole propionic acid) receptors and the kainate ...
