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5 days ago · Neurotransmitters articles from across Nature Portfolio. Neurotransmitters are biological molecules that are secreted by neurons and that alter the behaviour of their target neurons or effector cells.
8 hours ago · Serotonin (/ ˌ s ɛr ə ˈ t oʊ n ɪ n, ˌ s ɪər ə-/) or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.Its biological function is complex, touching on diverse functions including mood, cognition, reward, learning, memory, and numerous physiological processes such as vomiting and vasoconstriction.
- 5-HT, 5-Hydroxytryptamine, Enteramine, Thrombocytin, 3-(β-Aminoethyl)-5-hydroxyindole, Thrombotonin
- MAO
- system-wide
4 days ago · Several genes involved in the regulation of dopamine have been implicated in ADHD, further supporting the neurotransmitter imbalance theory. Research has identified specific genetic variants associated with ADHD. These include genes related to the dopamine transporter (DAT1), dopamine receptor (DRD4), and other neurotransmitter systems.
1 day ago · This work exposes a major impact of peroxisomal transporter loss on mitochondrial dynamics in mouse and C. elegans models of X-ALD, as well as in patient fibroblasts. It further unveils potential mitochondrial disease markers in patient CSF, holding promise for monitoring disease progression and alterations in clinical trials.
3 days ago · This review covers the most important PET tracers that have been used to image pain including tracers for fundamental biological processes such as glucose metabolism and cerebral blood flow, to receptor-specific tracers such as ion channels and neurotransmitters.
4 days ago · The high expression of the choline transporter in the BBB has also been explored for brain targeting. Choline is an essential amino acid and a precursor of the neurotransmitter acetylcholine produced by cholinergic neurons that play an important role in learning and memory [ 123 ].
5 days ago · Synaptic transmission is energetically costly. Myeong et al. demonstrate that hippocampal synapses can bypass glycolysis using oxidative fuels. Mitochondria, rather than glycolysis, control the spatiotemporal properties of vesicle release and ultrafast endocytosis. Mitochondrial localization in nerve terminals enhances vesicle release and reuptake, thus representing a form of synaptic plasticity.
