Search results
Apr 27, 2024 · The two main drugs used for the treatment of Chagas disease are benznidazole and nifurtimox. These medications are most effective in the acute phase of the infection, but they can also be used in the chronic phase. Benznidazole and nifurtimox work by killing the parasite that causes Chagas disease.
Apr 14, 2024 · Chagas disease can be cured if the treatment (benznidazole or nifurtimox) is administered in the acute phase of the disease, shortly after the initial infection occurs, or when it is administered to children.
Apr 26, 2024 · CD-positive patients could enter a drug observed treatment. While, in 2018, Benznidazole (BNZ) was provided as the first-line drug by the government, nifurtimox (NFX) was administered in 2020. Results: Of 121 individuals treated with BNZ, 79 (65%) suffered from at least one adverse event (AE).
4 days ago · In the U.S., two long-standing drugs have had FDA approval: benznidazole and nifurtimox, which can beat back the parasite but don’t always eradicate it. The medications can have serious side effects, and are most effective if given early: Babies born with Chagas have a 90% cure rate if treated within their first year of life.
May 3, 2024 · The electrochemical behavior of Nifurtimox, the anti-chagasic reference drug, was evaluated under the same experimental conditions. Nifurtimox also showed this reversible reduction process to generate the nitro anion radical, which agrees with their principal mechanism of action.
3 days ago · PMID: 31643176. Bookshelf ID: NBK547852. Excerpt. LiverTox ® provides up-to-date, unbiased and easily accessed information on the diagnosis, cause, frequency, clinical patterns and management of liver injury attributable to prescription and nonprescription medications and selected herbal and dietary supplements.
Apr 17, 2024 · The drugs currently accepted for treatment of Chagas disease are Nifurtimox manufactured by Bayer Health Care as Lampit®, and Benznidazole manufactured by Roche as Rochagan® or Radanil®.
