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Dec 20, 2021 · Breastmilk concentrations of nifurtimox ranged from nonquantifiable (<0.55 mg/L) to 8.2 mg/L. [ 4] Ten women were receiving a median dose of nifurtimox of 9.75 mg/kg daily donated 1 or 2 milk samples at various times after a dose at steady state. The median nifurtimox concentration in milk was 2.15 mg/L (interquartile range 1.32 to 4.55 mg/L).
ニフルチモックス (Nifurtimox)は シャーガス病 と アフリカ睡眠病 の治療に用いられる医薬品である [1] [2] 。. アフリカ睡眠病には ニフルロチモックス・エフルロチン併用療法 で エフロルニチン と共に用いられる [2] 。. シャーガス病の治療には、 ベンズニダ ...
Nifurtimox. In Meyler's Side Effects of Drugs (Sixteenth Edition), 2016. General information. Nifurtimox is used to treat Chagas’ disease (American trypanosomiasis) [1, 2].For treatment of the acute phase and in congenital cases the recommended dosage is 8–10 mg/kg/day, divided into two or three daily doses, for 30–60 consecutive days.
Melarsoprol is an arsenic -containing medication used for the treatment of sleeping sickness (African trypanosomiasis). [1] It is specifically used for second-stage disease caused by Trypanosoma brucei rhodesiense when the central nervous system is involved. [1] For Trypanosoma brucei gambiense, eflornithine or fexinidazole is usually preferred ...
Abdominal pain, nausea / vomiting, loss of appetite, headache, fever, dizziness, or diarrhea may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Loss of ...
Contraindications. Hypersensitivity to nifurtimox or any of the excipients. Alcohol consumption during treatment . Cautions. Genotoxicity has been demonstrated in humans, in vitro in several bacterial species and mammalian cell systems, and in vivo in rodents; a study in treated children with Chagas disease aged 7 months to 14 years demonstrated a 13-fold increase in chromosomal aberrations
Guarde las tabletas de nifurtimox a una temperatura ambiente de 68°F a 77°F (de 20°C a 25°C). Mantenga este producto en el envase original herméticamente cerrado. Si el envase tiene un pequeño paquete de agente de secado (llamado desecante ), no lo deseche. El desecante protege al medicamento contra la humedad.
