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Nifurtimox has also been used to treat African trypanosomiasis (sleeping sickness) and is active in the second stage of the disease (central nervous system involvement). When nifurtimox is given on its own, about half of all patients will relapse, but the combination of melarsoprol with nifurtimox appears to be efficacious.
Aug 24, 2020 · FDA Approves LAMPIT (Nifurtimox) for the Treatment of Chagas Disease in Pediatric Patients. On August 6, 2020, the US Food and Drug Administration (FDA) approved LAMPIT (nifurtimox) for the treatment of Chagas disease (American Trypanosomiasis), caused by Trypanosoma cruzi, in pediatric patients (birth to less than 18 years of age and weighing ...
Nifurtimox. In Meyler's Side Effects of Drugs (Sixteenth Edition), 2016. Observational studies. In 30 patients with arsenic-resistant trypanosomiasis in Zaire who were given a high dose of nifurtimox, 30 mg/kg/day, one died after a period of confusion and coma and eight developed neurological reactions, namely confusion, tremor, vertigo, and convulsions.
Side Effects. Abdominal pain, nausea / vomiting, loss of appetite, headache, fever, dizziness, or diarrhea may occur. If any of these effects last or get worse, tell your doctor or pharmacist ...
Sep 19, 2023 · Nifurtimox is a medication used to treat Chagas disease, also known as American trypanosomiasis, in pediatric patients. Nifurtimox is under investigation and not yet approved for the treatment of Chagas disease in adults. Common side effects of nifurtimox include vomiting, abdominal pain, decreased appetite, nausea, diarrhea, headache, dizziness, fever (pyrexia), rash, hives (urticaria ...
Nifurtimox wurde in den 1960er Jahren unter der Bezeichnung „Bayer 2502“ bei der Bayer AG entwickelt. Seit 1967 wird der Stoff gegen die Chagas-Krankheit eingesetzt; er ist neben Benznidazol die einzige Substanz, die zur Behandlung dieser Krankheit zur Verfügung steht. Derzeit sind keine Nifurtimox-Präparate in Deutschland, Österreich ...
