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  1. A drug overdose (overdose or OD) is the ingestion or application of a drug or other substance in quantities much greater than are recommended. Typically it is used for cases when a risk to health will potentially result. An overdose may result in a toxic state or death.

  2. Sep 1, 2020 · Overdose (OD) happens when a toxic amount of a drug, or combination of drugs overwhelms the body. People can overdose on lots of things, including alcohol, Tylenol, opioids or a mixture of drugs. Opioid overdoses happen when there are so many opioids or a combination of opioids and other drugs in the body that the victim is not responsive to ...

  3. Drug Overdose Deaths Remained High in 2021. More than one million people have died since 1999 from a drug overdose. 1 In 2021, 106,699 drug overdose deaths occurred in the United States. The age-adjusted rate of overdose deaths increased by 14% from 2020 (28.3 per 100,000) to 2021 (32.4 per 100,000). Opioids—mainly synthetic opioids (other ...

  4. A drug is any substance that can change how a person’s body and mind work. CDC’s Division of Overdose Prevention provides data on use and overdoses involving a variety of drugs, such as prescription opioids, heroin, fentanyl, cocaine, methamphetamine, and marijuana.

  5. Evidence-Based Strategies. Resources equip and inform states, territories, and local jurisdictions and provide support to overdose prevention programs. More. Resource Center. Videos, social media graphics, press releases, and online tools inform, supplement, and raise awareness about overdose prevention efforts. More. Last Reviewed: January 2, 2024

  6. Mar 2, 2022 · Statements and Releases. Drug overdose deaths have reached a historic high, devastating families and communities. More than 104,000 Americans died due to a drug overdose in the 12-month period...

  7. Jan 4, 2023 · An opioid overdose happens when opioids negatively affect the part of your brain that regulates breathing, resulting in ineffective breathing. It leads to death if it isn’t treated in time. A person experiencing an opioid overdose needs naloxone and immediate medical care to prevent death.

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