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Paraneoplastic syndromes of the nervous system
Paraneoplastic syndromes of the nervous system are a group of rare conditions that develop in some people who have cancer. In addition to the nervous system, paraneoplastic syndromes also can affect other organ systems including hormones, skin, blood and joints.
Paraneoplastic syndromes of the nervous system occur when cancer-fighting agents of the immune system also attack parts of the brain, spinal cord, peripheral nerves or muscle.
Depending on where the nervous system is affected, paraneop...
When to seek medical or mental health expertAlways seek the advice of your physician or other qualified health provider with any questions you may have regarding your health. Never disregard professional medical advice or delay in seeking it because of something you have read on the community.Symptoms of paraneoplastic syndromes of the nervous system can develop relatively quickly, often over days to weeks. They often begin even before a cancer is diagnosed.
Symptoms vary depending on the body part being injured, and may include:
- Trouble walking.
- Trouble with balance.
- Loss of muscle coordination.
- Loss of muscle tone or weakness....
Paraneoplastic syndromes of the nervous system are not caused by cancer cells directly or by the cancer spreading, known as metastasis. They're also not caused by other complications, such as infections or treatment side effects. Instead, the syndromes occur alongside the cancer as a result of the activation of your immune system.
Researchers believe that paraneoplastic syndromes of the nervous system are caused by cancer-fighting abilities of the immune system. In particular, antibodies and certain white b...
Treatment of paraneoplastic syndromes of the nervous system involves treating the cancer. Sometimes treatment also involves suppressing the immune response that's causing your symptoms. Your treatment depends on the type of paraneoplastic syndrome you have. It may include the following options.
Medications
In addition to cancer treatments, such as chemotherapy, your healthcare professional may prescribe one or more medicines. These medicines can help stop your immune system from dam...
For informational purposes only and not a substitute for professional medical advice, diagnosis, or treatment.
© Mayo Clinic
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