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  1. Samantha Who? is a TV series starring Christina Applegate as a woman who loses her memory after a car accident and tries to rebuild her life. The show features a cast of quirky characters, a mystery plot and a romantic subplot.

    • (11K)
    • 2007-10-15
    • Comedy, Mystery, Romance
    • 22
  2. Samantha Who? is an American television sitcom that originally aired on ABC from October 15, 2007, to July 23, 2009. The series was created by Cecelia Ahern and Donald Todd, who also served as producers.

    • Jan Stevens
    • Sitcom
  3. Watch the official Samantha Who? online at ABC.com. Get exclusive videos, blogs, photos, cast bios, free episodes.

  4. Samantha Who? is a sitcom about a woman who regains her memory after a car accident and tries to become a better person. The show ran for two seasons and stars Christina Applegate, Jennifer Esposito, Melissa McCarthy and others.

    • Christina Applegate
    • 2
  5. Samantha Who? is a comedy series about a woman who wakes up from a coma and tries to change her life. You can buy or rent the show on various platforms, or watch it for free on TV.

    • (165)
    • Samantha Newly; Andrea Belladonna; Howard
    • TV-14
    • 2007
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  7. Samantha Who? is a comedy series about a woman with amnesia who tries to rebuild her life. See the list of episodes, ratings, and summaries of each season and episode on IMDb.

  8. Samantha Who? is a comedy series starring Christina Applegate as a woman with amnesia who tries to be a better person. Read critics' reviews and find out where to watch season 1 on Vudu, Prime Video, or Apple TV.

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