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Mar 2, 2020 · SAPHO syndrome is a rare disorder that involves a combination of signs and symptoms affecting the joints, bones, and skin. People with SAPHO syndrome may experience inflammation of the joints...
Summary. SAPHO syndrome involves any combination of: Synovitis (inflammation of the joints), Acne, Pustulosis (thick yellow blisters containing pus) often on the palms and soles, Hyperostosis (increase in bone substance) and Osteitis (inflammation of the bones). The cause of SAPHO syndrome is unknown..
Jul 23, 2020 · Synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome is a constellation of dermatological and osteoarticular symptoms. The pathogenesis of SAPHO is unknown, but infectious, genetic, immunological and environmental factors may play a role.
Oct 27, 2023 · SAPHO syndrome, an acronym for synovitis, acne, pustular lesions, hyperostosis, and osteitis, is a rare, complex, and chronic inflammatory rheumatic disease that often follows a relapsing course [ 1, 2, 3, 4 ].
Dec 26, 2023 · Synovitis acne pustulosis hyperostosis osteitis (SAPHO) is a rare heterogeneous disease of unknown aetiopathology. Externally validated and internationally agreed diagnostic criteria or outcomes and, as a result, prospective randomised controlled trials in SAPHO are absent. Consequently, there is no agreed treatment standard.
Sep 24, 2020 · PMID: 32974863. The Diagnosis and Treatment of Adult Patients with SAPHO Syndrome: Controversies Revealed in a Multidisciplinary International Survey of Physicians. Victoria Furer, 1 Mitsumasa Kishimoto, 2 Shigeyoshi Tsuji, 3 Yoshinori Taniguchi, 4 Yoko Ishihara, 5 Tetsuya Tomita, 6 Philip S. Helliwell, 7 and Ori Elkayam 1.
Oct 27, 2023 · PMID: 37889264. DOI: 10.1007/s00296-023-05491-3. Abstract. This review provides an overview of SAPHO (Synovitis, Acne, Pustulosis, Hyperostosis, and Osteitis), a rare autoinflammatory disease that primarily affects bones, skin, and joints.
