Search results
Jan 21, 2022 · The SAPHO syndrome was given its acronymic name based upon the presence of synovitis, acne, pustulosis, hyperostosis, and osteitis in the patients described in early reports. It is a rare inflammatory disorder of bone, joints, and skin, which was first described as a syndrome in 1987 .
- What Is Sapho Syndrome?
- How Is The Diagnosis Made?
- Treatment
SAPHO syndrome is characterised by any combination of: 1. Synovitis (inflammationof the joints) 2. Acne (conglobata or fulminans) 3. Pustulosis (thick yellow blisters containing pus) often on the palms and soles and similar to palmoplantar pustular psoriasis) 4. Hyperostosis (increase in bone substance) 5. Osteitis (inflammation of the bones) The c...
SAPHO syndrome is suspected when a patient presents with a pustular skin disease in association with rheumaticpain. Magnetic resonance imaging (MRIscan) shows inflammation of the bone marrow or joints at characteristic sites such as the collar bone, breast bone, pelvis, heel, and lower jaw.
SAPHO has no specific drug treatment. It can be a chronic condition but eventually self-heals. A rheumatologist may manage the joint symptoms, often prescribing nonsteroidal anti-inflammatory drugs or sulfonamides such as sulfasalazine. A dermatologist may use vitamin A derivatives (oral retinoids) to treat the acne (isotretinoin) and the palmoplan...
SAPHO syndrome is a rare disorder that involves a combination of signs and symptoms affecting the joints, bones, and skin. People with SAPHO syndrome may experience inflammation of the joints...
People also ask
What does Sapho stand for?
What is SAPHO syndrome?
Are biological treatments a viable alternative for SAPHO patients?
What is the pathogenesis of Sapho?
SAPHO syndrome includes a variety of inflammatory bone disorders that may be associated with skin changes. These diseases share some clinical, radiologic, and pathologic characteristics. An entity initially known as chronic recurrent multifocal osteomyelitis was first described in 1972.
- Synovitis-acne-pustulosis-hyperostosis-osteitis syndrome
Jul 23, 2020 · Synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome is a constellation of dermatological and osteoarticular symptoms. The pathogenesis of SAPHO is unknown, but infectious, genetic, immunological and environmental factors may play a role.
Oct 27, 2023 · SAPHO syndrome, an acronym for synovitis, acne, pustular lesions, hyperostosis, and osteitis, is a rare, complex, and chronic inflammatory rheumatic disease that often follows a relapsing course [ 1, 2, 3, 4 ].
Apr 13, 2022 · Synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome is a rare autoinflammatory disease characterized by dermatological disorders and osteoarticular inflammatory lesions. This article reviews the application of biologics and other treatments based on the therapeutic target and the size of molecules in SAPHO syndrome.
