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  1. Schizophrenia - Wikipedia

    en.wikipedia.org › wiki › Schizophrenia

    4 days ago · Repeated relapses worsen the long-term outlook and the risk of relapse following a second episode is high, and long-term treatment is usually recommended. [180] [181] Tobacco smoking increases the metabolism of some antipsychotics, by strongly activitating CYP1A2 , the enzyme that breaks them down, and a significant difference is found in these ...

  2. Major depressive disorder - Wikipedia

    en.wikipedia.org › wiki › Major_depressive_disorder

    5 days ago · Major depressive disorder (MDD), also known simply as depression, is a mental disorder characterized by at least two weeks of pervasive low mood.Low self-esteem, loss of interest in normally enjoyable activities, low energy, and pain without a clear cause are common symptoms.

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