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  1. African Trypanosomiasis, also known as “sleeping sickness”, is caused by microscopic parasites of the species Trypanosoma brucei. It is transmitted by the tsetse fly (Glossina species), which is found only in sub-Saharan Africa.

  2. Trypanosoma brucei is a species of parasitic kinetoplastid belonging to the genus Trypanosoma that is present in sub-Saharan Africa. Unlike other protozoan parasites that normally infect blood and tissue cells, it is exclusively extracellular and inhabits the blood plasma and body fluids.

  3. May 2, 2023 · HAT takes 2 forms, depending on the parasite subspecies: Trypanosoma brucei gambiense, found in 24 countries of west and central Africa, currently accounts for 92% of reported cases and causes a chronic illness. A person can be infected for months or even years without major signs or symptoms.

  4. Humans are considered the main reservoir for Trypanosoma brucei gambiense, but this species can also be found in animals, including primates and ungulates. Domestic cattle are thought to be the most epidemiologically-relevant animal reservoir of T. b. rhodesiense.

  5. Trypanosomiasis is a serious type of parasitic infection that affects different parts of your body as it spreads, including your: Skin. Blood. Lymph nodes. Brain and the fluid surrounding your brain and spinal cord (cerebrospinal fluid). It spreads through the bites of tsetse flies that live in equatorial Africa.

  6. Trypanosoma brucei causes African trypanosomiasis in humans and nagana in domestic animals. This vector-borne parasite, transmitted by the tsetse fly, affects rural areas in sub-Saharan Africa. When injected by the fly, metacyclic-form parasites are introduced into the host dermis and then disseminate into the bloodstream as replicative long ...

  7. African trypanosomiasis, also known as African sleeping sickness or simply sleeping sickness, is an insect-borne parasitic infection of humans and other animals. [3] . It is caused by the species Trypanosoma brucei. [3] . Humans are infected by two types, Trypanosoma brucei gambiense (TbG) and Trypanosoma brucei rhodesiense (TbR). [3] .

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