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Apr 18, 2024 · Author(s): Gao, Zi | Advisor(s): Wang, Yinsheng | Abstract: Guanine quadruplex (G4) structures are nonconical DNA conformations that play crucial roles in various cellular processes, including DNA replication and transcription regulation.
Apr 18, 2024 · The proto-oncogene KIT encodes for a tyrosine kinase receptor, which is a clinically validated target for treating gastrointestinal stromal tumors. The KIT promoter contains a G-rich domain within a relatively long sequence potentially able to form three adjacent G-quadruplex (G4) units, namely, K2, SP, and K1. These G4 domains have been studied mainly as single quadruplex units derived from ...
May 3, 2024 · Oncogenic BRAF mutations contribute to the development of a number of cancers, and small-molecule BRAF inhibitors have been approved by the Food and Drug Administration (FDA) for anticancer therapy. In this study, we employed two targeted quantitative proteomics approaches for monitoring separately the alterations in protein expression and ATP binding affinities of kinases in cultured human ...
Apr 27, 2024 · Lifan Zhu Mingzhong Wang Yinsheng Xu Xianghua Zhang Ping Lu. Materials Science. Journal of the American Ceramic Society. 2022; 11. PDF. Save.
4 days ago · Fan Zhendong (Chinese: 樊振东; pinyin: Fán Zhèndōng; born 22 January 1997) is a Chinese professional table tennis player. After joining the Chinese National Table Tennis Team in 2012 as the youngest member of the team, he went on to become the youngest ITTF World Tour Champion and the youngest World Table Tennis Champion .
- 1.73 m (5 ft 8 in)
- 77 kg (170 lb)
- 樊振东
6 days ago · Xu Xin ( simplified Chinese: 许昕; traditional Chinese: 許昕; pinyin: Xǔ Xīn; born 8 January 1990) is a Chinese professional table tennis player who is currently ranked world No. 103 as of May 2023 for men's singles by the International Table Tennis Federation (ITTF). He first reached his career-high singles ranking of world No. 1 in ...
Apr 29, 2024 · The attributes of diversity and concealment pose formidable challenges in the accurate detection and efficacious management of distresses within subgrade structures. The onset of subgrade distresses may precipitate structural degradation, thereby amplifying the frequency of traffic incidents and instigating economic ramifications. Accurate and timely detection of subgrade distresses is ...
