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- Researchers have not found one single cause of autism. Several factors could play a role in its development. They include: having a twin or older sibling with autism older parental age at the time of conception brain growth disruptions in early development preterm birth
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Jan 6, 2018 · Genetics. Several different genes appear to be involved in autism spectrum disorder. For some children, autism spectrum disorder can be associated with a genetic disorder, such as Rett syndrome or fragile X syndrome. For other children, genetic changes (mutations) may increase the risk of autism spectrum disorder.
Mar 31, 2021 · Autism is complex, and no two autistic people are the same. Because of this, researchers believe there are probably many causes of autism, including genetic and environmental factors. So...
Aug 20, 2019 · Genetic modifiers in autism spectrum disorder. Autism is estimated to be 40–80% heritable. However, both genetic and non-genetic factors modulate the penetrance of risk genes, resulting in a highly heterogeneous disease phenotype for similar pathogenic variants.
- Lauren Rylaarsdam, Alicia Guemez-Gamboa
- 10.3389/fncel.2019.00385
- 2019
- Front Cell Neurosci. 2019; 13: 385.
Aug 20, 2021 · The term incorporates several conditions such as idiopathic forms, including autism, Asperger syndrome and Pervasive Developmental Disorder - Not Otherwise Specified, and Childhood Disintegrative Disorder and certain genetic disorders like Rett syndrome, which can exhibit autistic traits ( 3 ).
- Ann Katrin Sauer, Janelle E. Stanton, Sakshi Hans, Andreas M. Grabrucker
- 2021
Jul 4, 2011 · A new Stanford University School of Medicine study of twins suggests that non-genetic factors play an unexpectedly large role in determining autism risk, turning upside down recent assumptions about the cause of this common, disabling developmental disorder.
For some people, a high risk for ASD can be associated with a genetic disorder, such as Rett syndrome or fragile X syndrome. For the majority of autism, multiple changes in other regions of your DNA increase the risk of autism spectrum disorder.
There are many known environmental, genetic, and biological causes of autism. Research indicates that genetic factors are predominate in the appearance of autism; however, the heritability of autism is complex, and many of the genetic interactions involved are unknown. [1] .
