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  1. 2 days ago · The statements are by nature inherent in risks, uncertainties and other matters that are difficult to predict or out of control. The actual results may therefore differ from the expectations expressed. Contacts. Jakob Knudsen, CEO, +45 2226 1355, jk@virogates.com; Attachments. 20240415-Company Announcement 3 - FDA Q-Sub.pdf

  2. 3 days ago · The first is classical PNH, in which patients have clinical manifestations of hemolysis or thrombosis, the PNH clone is usually >50%, and bone marrow examination generally reveals erythroid hyperplasia; the second is PNH in the setting of another bone marrow failure syndrome, such as aplastic anemia or myelodysplastic syndrome, in which ...

  3. 3 days ago · Introduction Administration of oxygen therapy is common, yet there is a lack of knowledge on its ability to prevent cellular hypoxia as well as on its potential toxicity. Consequently, the optimal oxygenation targets in clinical practice remain unresolved. The novel PpIX technique measures the mitochondrial oxygen tension in the skin (mitoPO2) which allows for non-invasive investigation on the ...

  4. 2 days ago · Finally, two separate modelling pathways were used to estimate sepsis-related mortality fractions and infectious syndromes' contributions to sepsis-related mortality, ensuring accuracy and comprehensiveness in estimating pathogen burdens within the GBD framework. Further details on this approach are provided in the appendix (pp 8–11).

  5. 3 days ago · BACKGROUND AND OBJECTIVES:. Time to clinical stability (TCS) is a commonly used outcome in adults with community-acquired pneumonia (CAP), yet few studies have evaluated TCS in children. Our objective was to determine the association between TCS and disease severity in children with suspected CAP, as well as factors associated with reaching early stability.METHODS:. This is a prospective ...

  6. Global maternal and neonatal death rates are unacceptably high1–3 and these deaths are due to complications of pregnancy and childbirth, mostly from preventable or treatable causes. Most of these deaths (94%) are within low-income and middle-income countries and could be prevented through timely interventions.

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